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In this paper, the use of the MaxInf Principle in real optimization problems is investigated for engineering applications, where the current design solution is actually an engineering approximation. In industrial manufacturing, multibody system simulations can be used to develop new machines and mechanisms by using virtual prototyping, where an axiomatic design can be employed to analyze the independence of elements and the complexity of connections forming a general mechanical system. In the classic theories of Fisher and Wiener-Shannon, the idea of information is a measure of only probabilistic and repetitive events. However, this idea is broader than the probability alone field. Thus, the Wiener-Shannon's axioms can be extended to non-probabilistic events and it is possible to introduce a theory of information for non-repetitive events as a measure of the reliability of data for complex mechanical systems. To this end, one can devise engineering solutions consistent with the values of the design constraints analyzing the complexity of the relation matrix and using the idea of information in the metric space. The final solution gives the entropic measure of epistemic uncertainties which can be used in multibody system models, analyzed with an axiomatic design. [ABSTRACT FROM AUTHOR]