1. Maternal and fetal exposure to parabens in a multiethnic urban U.S. population
- Author
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Rolf U. Halden, Mudar Dalloul, Ovadia Abulafia, Benny F. G. Pycke, and Laura A. Geer
- Subjects
Adult ,Adolescent ,Urban Population ,Population ,New York ,Physiology ,Parabens ,Urine ,Umbilical cord ,Article ,Toxicology ,chemistry.chemical_compound ,Young Adult ,Pregnancy ,Blood plasma ,medicine ,Humans ,education ,lcsh:Environmental sciences ,General Environmental Science ,lcsh:GE1-350 ,Fetus ,education.field_of_study ,business.industry ,medicine.disease ,Fetal Blood ,United States ,Paraben ,medicine.anatomical_structure ,chemistry ,Maternal Exposure ,Cord blood ,Body Burden ,Female ,business - Abstract
Fetal exposure to five parabens was investigated due to their endocrine-disrupting potential and possible impact on fetal development. Body burdens occurring from real-world exposures were determined typically as total concentrations after conjugate hydrolysis in 181 maternal urine and 38 umbilical cord blood plasma samples from a multiethnic cohort of 185 predominantly-black, pregnant women recruited in Brooklyn, New York between 2007/9. For 33 participants, both sample types (maternal urine and cord blood) were available. Methyl- (MePB), ethyl- (EtPB), propyl- (PrPB), butyl- (BuPB), and benzylparaben (BePB) were detected in 100, 73.5, 100, 66.3 and 0.0% of the urine samples at median concentrations of 279, 1.44, 75.3, 0.39, and
- Published
- 2015