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Your search keyword '"Alanine transaminase (ALT)"' showing total 2 results
Start Over Descriptor "Alanine transaminase (ALT)" Journal environmental toxicology & pharmacology
2 results on '"Alanine transaminase (ALT)"'

1. Tetrachlorobenzoquinone induces acute liver injury, up-regulates HO-1 and NQO1 expression in mice model: The protective role of chlorogenic acid.

Author

Xu, Demei, Hu, Lihua, Xia, Xiaomin, Song, Jianbo, Li, Lingrui, Song, Erqun, and Song, Yang

Subjects
*CHLORANIL, *LIVER injuries, *LABORATORY mice, *GENE expression, *GENETIC regulation, *CHLOROGENIC acid
Abstract

Highlights: [•] TCBQ-intoxication elevated ALT, AST activities and TBIL content. [•] TCBQ-intoxication induced necrosis and inflammatory in liver section. [•] TCBQ-intoxication increased ROS, TBARS and decreased antioxidant activities. [•] TCBQ-intoxication induced HO-1 and NQO1 expression. [•] Pretreatment of CGA relieved TCBQ-induced liver damage remarkably. [Copyright &y& Elsevier]

Published
2014
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2. Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model.

Author

Wang, Xinhui, Gong, Guoqing, Yang, Wenhui, Li, Yunzhan, Jiang, Meiling, and Li, Linlin

Subjects
*FIBROSIS, *FLAVONOLS, *LIVER physiology, *CARBON tetrachloride, *LABORATORY rats, *LIPID peroxidation (Biology), *THERAPEUTICS
Abstract

Highlights: [•] The protective effect of galangin against carbon tetrachloride-induced liver fibrosis in rats was investigated. [•] Galangin inhibited lipid peroxidation, HSCs proliferation and collagen gene expression. [•] For the first time, we confirmed that galangin can ameliorate liver fibrosis. [ABSTRACT FROM AUTHOR]

Published
2013
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