1. Prevalence of anaemia and associated factors among people with pulmonary tuberculosis in Uganda
- Author
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Joseph Baruch Baluku, Ernest Mayinja, Pallen Mugabe, Kauthrah Ntabadde, Ronald Olum, and Felix Bongomin
- Subjects
Adult ,Male ,Adolescent ,Coinfection ,Epidemiology ,Anemia ,HIV Infections ,Young Adult ,Cross-Sectional Studies ,Infectious Diseases ,Socioeconomic Factors ,Thinness ,Risk Factors ,Prevalence ,Humans ,Female ,Uganda ,Tuberculosis, Pulmonary - Abstract
Anaemia predicts delayed sputum conversion and mortality in tuberculosis (TB). We determined the prevalence and factors associated with anaemia among people with TB at the National Tuberculosis Treatment Centre in Uganda. People with bacteriologically confirmed TB were consecutively enrolled in a cross-sectional study between August 2017 and March 2018. Blood samples were tested for a full blood hemogram, HIV infection, and CD4+ and CD8+ T-cell counts. Anaemia was defined as a haemoglobin level of P < 0.001), low CD4:CD8 ratio (OR 2.54, 95% CI 1.07–6.04, P = 0.035) and microcytosis (OR 4.23, 95% CI 2.17–8.25, P < 0.001). Anaemia may be associated with the features of severe TB disease and should be considered in TB severity scores.
- Published
- 2022
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