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Your search keyword '"D'Onofrio, Gianluca"' showing total 5 results
Start Over Author "D'Onofrio, Gianluca" Journal epilepsia open
5 results on '"D'Onofrio, Gianluca"'

1. Myoclonus: Differential diagnosis and current management

Author

Riva, Antonella, primary, D'Onofrio, Gianluca, additional, Ferlazzo, Edoardo, additional, Pascarella, Angelo, additional, Pasini, Elena, additional, Franceschetti, Silvana, additional, Panzica, Ferruccio, additional, Canafoglia, Laura, additional, Vignoli, Aglaia, additional, Coppola, Antonietta, additional, Badioni, Valeria, additional, Beccaria, Francesca, additional, Labate, Angelo, additional, Gambardella, Antonio, additional, Romeo, Antonino, additional, Capovilla, Giuseppe, additional, Michelucci, Roberto, additional, Striano, Pasquale, additional, and Belcastro, Vincenzo, additional

Published
2024
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2. A European pilot study in Dravet Syndrome to delineate what really matters for the patients and families.

Author

Chemaly, Nicole, Kuchenbuch, Mathieu, Teng, Théo, Marie, Elodie, D'Onofrio, Gianluca, Lo Barco, Tommaso, Brambilla, Isabella, Flege, Silke, Hallet, Anne‐Sophie, and Nabbout, Rima

Subjects
PATIENTS' families, PILOT projects, PATIENT advocacy, PRESSURE groups, PEOPLE with epilepsy
Abstract

We aimed to identify caregivers' opinions on the outcome measures that matter in clinical trials in individuals with Dravet syndrome (DS). We conducted a prospective European multicenter study based on an 11 closed questions survey developed by the French reference center for rare epilepsies and DS patients' advocacy groups. Items included questions on seizures and daily life outcomes that a clinical trial on a therapy for individuals with DS should target. Statistical analyses were performed to evaluate the impact of the country of residence and of the patients' age. The survey was answered by 153 caregivers (68%: France, 28%: Germany, and 24%: Italy) off individuals with DS. Individuals with DS included 86 males (mean age of 11.4 [interquartile: 7‐20.4] years). Families ranked as important almost all the items proposed. However, items related to daily life had the highest rank in all three countries compared to items about seizures (P = 0.02). Increase in individuals' age was associated with a higher age at diagnosis (ρ = 0.26, P = 0.02), and a lower impact of seizure duration (ρ = −0.25, P = 0.005) and on the need of hospital referral (ρ = −0.26, P = 0.005). These data can help tailor patient‐centered outcome measures in future clinical and real‐life trials for DS. [ABSTRACT FROM AUTHOR]

Published
2024
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3. A real‐life pilot study of the clinical application of pharmacogenomics testing on saliva in epilepsy

Author

Riva, Antonella, primary, Roberti, Roberta, additional, D’Onofrio, Gianluca, additional, Stella Vari, Maria, additional, Amadori, Elisabetta, additional, De Giorgis, Valentina, additional, Cerminara, Caterina, additional, Specchio, Nicola, additional, Pietrafusa, Nicola, additional, Tombini, Mario, additional, Assenza, Giovanni, additional, Cappanera, Silvia, additional, Marini, Carla, additional, Rasmini, Paolo, additional, Veggiotti, Pierangelo, additional, Zara, Federico, additional, Russo, Emilio, additional, and Striano, Pasquale, additional

Published
2023
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