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Your search keyword '"Elger, Christian E."' showing total 34 results
Start Over Author "Elger, Christian E." Journal epilepsy & behavior
34 results on '"Elger, Christian E."'

5. Low CSF CD4/CD8 + T-cell proportions are associated with blood–CSF barrier dysfunction in limbic encephalitis

Author

Hansen, Niels, primary, Schwing, Kerstin, additional, Önder, Demet, additional, Widman, Guido, additional, Leelaarporn, Pitshaporn, additional, Prusseit, Indra, additional, Surges, Rainer, additional, Melzer, Nico, additional, Gross, Catharina, additional, Becker, Albert J., additional, Witt, Juri-Alexander, additional, Elger, Christian E., additional, and Helmstaedter, Christoph, additional

Published
2020
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14. Changes in hormone and lipid levels in male patients with focal seizures when switched from carbamazepine to lacosamide as adjunctive treatment to levetiracetam: A small phase IIIb, prospective, multicenter, open-label trial

Author

Elger, Christian E., primary, Rademacher, Michael, additional, Brandt, Christian, additional, Elmoufti, Sami, additional, Dedeken, Peter, additional, Eckhardt, Klaus, additional, Tennigkeit, Frank, additional, and De Backer, Marc, additional

Published
2016
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33. Which drug-induced side effects would be tolerated in the prospect of seizure control?

Author

Witt, Juri-Alexander, Elger, Christian E., and Helmstaedter, Christoph

Subjects
*DRUG side effects, *SPASMS, *DRUG therapy, *QUALITY of life, *PHARMACODYNAMICS, *SEIZURES (Medicine), *WEIGHT gain
Abstract

Abstract: There is ample evidence that side effects of antiepileptic pharmacotherapy negatively affect quality of life, adherence, and long-term retention. The study was set up to evaluate the anticipated tolerance of common side effects provided that a 50% or 100% reduction of seizure frequency would be achieved. An anonymous inquiry in 79 consecutive patients with epilepsy comprised questions regarding the severity of epilepsy/seizures and the perceived impact of seizures and drug treatment on daily functioning and a 10-tiered rating which assesses 11 common behavioral/psychiatric, cognitive, physiological, or physical side effects according to the degree to which they would be tolerated. Least acceptance was evident for psychiatric side effects followed by cognitive, physiological, and physical side effects. Weight gain and tiredness were the most tolerated side effects. The overall low acceptance of negative side effects was slightly higher in the case of a 100% vs. 50% seizure frequency reduction (28% vs. 21% of the maximum toleration score regarding all side effects). Surely, there is a trade-off between the severity of epilepsy, seizure control, and the acceptance of adverse treatment effects. However, the data disclose that psychiatric and cognitive side effects are least accepted. Thus, consideration of individual tolerance and monitoring of side effects in addition to seizures may increase adherence and therapy success. [Copyright &y& Elsevier]

Published
2013
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34. Face and facial expression memory in temporal lobe epilepsy patients: preliminary results

Author

Glogau, Sonja, Ellgring, Heiner, Elger, Christian E., and Helmstaedter, Christoph

Subjects
*TEMPORAL lobe epilepsy, *FACE, *FACIAL expression, *TEMPORAL lobe
Abstract

Right temporal lobe structures are involved in face and facial expression processing and in mnestic functions. Face and facial expression memory was investigated in 15 patients with left (LTLE) and 18 patients with right (RTLE) temporal lobe epilepsy as well as 13 healthy controls. Pairs of pictures combining four faces and four emotions had to be matched according to face identity or facial expression. In the memory tasks, the two pictures of a pair were divided by a memory interval of 2000 milliseconds, whereas in the perception tasks (control condition) both pictures were presented simultaneously. RTLE patients had significantly lower scores than healthy controls in face memory. LTLE patients had significantly lower scores than healthy controls in face and facial expression memory. The data confirm impaired face memory in RTLE patients and show that LTLE patients display deficits in face as well as in facial expression memory. Results are discussed according to functional reorganization, memory strategies, perception performance, naming problems, and group characteristics. [Copyright &y& Elsevier]

Published
2004
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