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Objective: The objective of this study is to compare the overall survival (OS) and the cancer-specific survival (CSS) for patients of T1aN0M0 glottic cancer who underwent laser surgery (LS) or radiation (RT). Methods: The data of the population-based analysis were extracted from the SEER database. The studies of the meta-analysis were identified through PubMed, EMBASE, and Cochrane databases. Cox regression analyses, the propensity score analysis (PSM), survival analyses, and the meta-analysis were performed. Results: In the population-based analysis, 2101 eligible patients were included. Multivariable Cox analyses indicated that patients accepting LS alone would obtain better OS (HR 0.77, 95% CI 0.61–0.98, p = 0.03) and CSS (HR 0.26, 95% CI 0.12–0.59, p = 0.001) than those of whom they accepted RT alone. Survival analyses before PSM and after PSM also indicated that patients who underwent LS alone would have better OS and CSS. In the meta-analysis, nine eligible studies were included. Results of the pooled effect showed that significant differences existed between LS and RT groups on OS (OR: 1.84, 95% CI 1.36–2.50, p < 0.001) and CSS (OR 3.84, 95% CI 1.17–12.52, p = 0.026), both distinctly favoring LS. Conclusions: Compared with RT, LS may acquire better survivals for patients with T1aN0M0 glottic cancer. Simultaneously, more multi-center randomized controlled trials would be warranted to prove the conclusion. [ABSTRACT FROM AUTHOR]

Hosseini et al. concluded that peritonsillar bupivacaine compared to acetaminophen obtained a better effect on managing postoperative pain, improving sedation, and suffering no complications. Therefore, it strongly indicated that Hosseini et al.'s study did not include sufficient cases undergoing tonsillectomy Third, in Hosseini et al.'s Table 1, the mean pain scores at 240 min and 360 min after the surgery were 1.20 ± 0.00 and 1.30 ± 0.00, respectively. References 1 Hosseini H, Shariatmadari M, Ayatollahi V, Vaziribozorg S, Meybodian M. Comparing the efficacy of peritonsillar injection of bupivacaine and intravenous acetaminophen on post-tonsillectomy pain in children. [Extracted from the article]

With great interest, we read the retrospective study about comparison of needle aspiration versus incision and drainage under local anaesthesia for the initial treatment of peritonsillar abscess (PTA) [[1]]. However, Wolf et al. demonstrated that needle aspiration is a tempting modality for treating PTA, but has the higher risks of residual and recurrent disease in comparison to incision and drainage [[5]]. 1 Mansour C, De Bonnecaze G, Mouchon E. Comparison of needle aspiration versus incision and drainage under local anaesthesia for the initial treatment of peritonsillar abscess. [Extracted from the article]