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31 results on '"Carrington, M"'

6. Cryoablation: safety of same day discharge

Author

Carrington, M, primary, Silverio Antonio, P, additional, Nunes-Ferreira, A, additional, Rodrigues, T, additional, Cunha, N, additional, Couto Pereira, S, additional, Brito, J, additional, Alves Da Silva, P, additional, Valente Silva, B, additional, Lima Da Silva, G, additional, Carpinteiro, L, additional, Cortez-Dias, N, additional, J Pinto, F, additional, and De Sousa, J, additional

Published
2021
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8. It is possible to predict mortality after ICD implantation?

Author

Carrington, M, primary, Silverio Antonio, P, additional, Nunes-Ferreira, A, additional, Rodrigues, T, additional, Couto Pereira, S, additional, Bernardes, A, additional, Lima Da Silva, G, additional, Magalhaes, A, additional, J Pinto, F, additional, De Sousa, J, additional, and Marques, P, additional

Published
2021
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15. P1720Survival analysis in a population of patients with cardiogenic shock after acute myocardial infarction: characterization of the population and identification of mortality predictors

Author

Da Conceicao Pedro Pais, J A, primary, Picarra, B, additional, Carrington, M, additional, Santos, A R, additional, Guerreiro, R A, additional, Bras, D, additional, Congo, K I S A, additional, Carvalho, J, additional, Neves, D, additional, and Aguiar, J, additional

Published
2019
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23. Standard vs. intensified management of heart failure to reduce healthcare costs: results of a multicentre, randomized controlled trial.

Author

Scuffham, P. A., Ball, J., Horowitz, J. D., Wong, C., Newton, P. J., Macdonald, P., McVeigh, J., Rischbieth, A., Emanuele, N., Carrington, M. J., Reid, C. M., Chan, Y. K., and Stewart, S.

Abstract

Aims To determine if an intensified form of heart failure management programme (INT-HF-MP) based on individual profiling is superior to standard management (SM) in reducing health care costs during 12-month follow-up (primary endpoint). Methods and results A multicentre randomized trial involving 787 patients (full analysis set) discharged from four tertiary hospitals with chronic HF who were randomized to SM (n=391) or INT-HF-MP (n=396). Mean age was 74 ± 12 years, 65% had HF with a reduced ejection fraction (31.4 ± 8.9%) and 14% were remote-dwelling. Study groups were well matched. According to Green, Amber, Red Delineation of rIsk And Need in HF (GARDIAN-HF) profiling, regardless of location, patients in the INT-HF-MP received a combination of face-to-face (home visits) and structured telephone support (STS); only 9% ('low risk') were designated to receive the same level of management as the SM group. The median cost in 2017 Australian dollars (A$1 equivalent to ∼EUR €0.7) of applying INT-HF-MP was significantly greater than SM ($152 vs. $121 per patient per month; P<0.001), However, at 12 months, there was no difference in total health care costs for the INT-HF-MP vs. SM group (median $1579, IQR $644 to $3717 vs. $1450, IQR $564 to $3615 per patient per month, respectively). This reflected minimal differences in all-cause mortality (17.7% vs. 18.4%; P=0.848) and recurrent hospital stay (18.6±26.5 vs. 16.6±24.8 days; P=0.199) between the INT-HF-MP and SM groups, respectively. Conclusion During 12-months follow-up, an INT-HF-MP did not reduce healthcare costs or improve health outcomes relative to SM. [ABSTRACT FROM AUTHOR]

Published
2017
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30. Standing at the crossroads between new and historically prevalent heart disease: effects of migration and socio-economic factors in the Heart of Soweto cohort study.

Author

Stewart S, Carrington M, Pretorius S, Methusi P, and Sliwa K

Subjects
Adult, Aged, Cohort Studies, Educational Status, Female, Humans, Life Style, Male, Middle Aged, Prevalence, Risk Factors, Socioeconomic Factors, South Africa, Urbanization, Diabetes Mellitus, Type 2 epidemiology, Diabetic Angiopathies epidemiology, Emigration and Immigration statistics & numerical data, Heart Diseases epidemiology, Hypertension epidemiology
Abstract

Aims: Migration, urbanization, and change in socio-economic factors have potentially profound effects on heart disease in low-to-middle income countries., Methods and Results: Chris Hani Baragwanath Hospital in Soweto, South Africa, provides health care to >1 million Africans. We systematically captured data from all de novo presentations of suspected heart disease (focusing on 'new' vs. historically prevalent forms) during 2006-2008. There were 3168 female (52 ± 18 years) vs. 2160 male (53 ± 17 years) cases. Overall, 999 (19%) presented with uncomplicated hypertension (n = 988) or type II diabetes, 1862 cases (35%) 'new' heart disease (1146 and 581 cases of hypertensive heart failure and coronary artery disease), and 2092 cases (39%) of historically prevalent heart disease (including 724 with primary valve disease and 502 idiopathic dilated cardiomyopathies). Level of education and non-communicable risk factors were important correlates of advanced disease. The rate of historically prevalent cases was higher in those aged 20-49 years (19-60 cases/100,000 population/annum) whilst being higher for "new" heart disease in those aged >50 years (155-343 cases/population/annum). Historically prevalent heart disease cases were younger [adjusted odds ratio (OR) 0.98, 95% 0.97-0.99 per year], more likely to be African (OR 4.59, 95% 2.76-7.60) while being less likely to originate from Soweto (OR 0.87, 95% 0.75-1.00) and be female (OR 0.67, 95% 0.49-0.92)., Conclusion: Dynamic socio-economic and lifestyle factors characteristic of epidemiological transition appear to have positioned the urban, mainly African community of Soweto at the crossroads between historically prevalent and 'new' forms of heart disease.

Published
2011
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31. Incidence and characteristics of newly diagnosed rheumatic heart disease in urban African adults: insights from the heart of Soweto study.

Author

Sliwa K, Carrington M, Mayosi BM, Zigiriadis E, Mvungi R, and Stewart S

Subjects
Adolescent, Adult, Aged, Echocardiography, Female, Humans, Incidence, Male, Middle Aged, Prognosis, Risk Factors, South Africa epidemiology, Urban Health, Young Adult, Calcinosis mortality, Heart Valve Diseases mortality, Rheumatic Heart Disease mortality
Abstract

Aims: Little is known on the incidence and clinical characteristics of newly diagnosed rheumatic heart disease (RHD) in adulthood from urban African communities in epidemiologic transition., Methods and Results: Chris Hani Baragwanath Hospital services the black African community of 1.1 million people in Soweto, South Africa. A prospective, clinical registry captured data from all de novo cases of structural and functional valvular heart disease (VHD) presenting to the Cardiology Unit during 2006/07. We describe in detail all cases with newly diagnosed RHD. There were 4005 de novo presentations in 2006/07 and 960 (24%) had a valvular abnormality. Of these, 344 cases (36%) were diagnosed with RHD. Estimated incidence of new cases of RHD for those aged >14 years in the region was 23.5 cases/100 000 per annum. Most were black African females (n = 234-68%) with a similar age profile to males [median 41 (interquartile range 30-55) years vs. 42 (interquartile range 31-55) years]. The predominant valvular lesion (n = 204, 59%) was mitral regurgitation (MR), with 48 (14%) and 43 (13%) cases, respectively, having combination lesions of aortic plus MR and mixed mitral VHD. Impaired systolic function was found in 28/204 cases (14%) of predominant MR and in 23/126 cases (18%) with predominant aortic regurgitation. Elevated right ventricular systolic pressure >35 mmHg (62 cases), atrial fibrillation (34 cases), and anaemia (27 cases) were found in 18, 10, and 8% of 344 RHD cases, respectively. Subsequent valve replacement/repair was performed in 75 patients (22%). A total of 90 cases (26%) were admitted within 30 months of initial diagnosis for suspected bacterial endocarditis., Conclusion: These data reveal a high incidence of newly diagnosed RHD within an adult urban African community. These data argue strongly for the first episode of RHD to be made a notifiable condition in high burden countries in order to ensure control of the disease through register-based secondary prophylaxis programmes.

Published
2010
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