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Vast progress has been made in the diagnosis and therapy of mycosis fungoides (MF), however only sparse information is provided in the literature regarding the patient's coping strategies with MF, its dermatological manifestations, the effect on one's appearance and its significance as a malignant disease. To examine the individuals' perception of their illness and coping strategies with MF, while comparing different groups of patients with regard to sex, age, illness duration and severity of the disease. 74 patients in various stages of MF participated in this study. The participants completed questionnaires concerning coping strategies (Ways of Coping Questionnaire) and illness perception (IPQ-R). A comparison based on sex, age, illness duration (0–3 years, 4–6 years, 7–10 years and >10 years) and illness severity (stage below IIB or stage IIB and above) was performed. Anova and Mann-Whitney U tests were used in the analysis. Women were found to report more illness-related symptoms (p=0.03) and experienced MF in a more prolonged and cyclical manner than men (p=0.04). Women expressed more feelings of anxiety and a depressed mood when asked about their illness in comparison with men (p=0.09). Furthermore, difference was seen in the number of symptoms reported with respect to disease severity (p=0.15). In addition, when reviewing the questionnaire results in relation to illness duration, a statistically significant difference was observed regarding sense of control over disease by treatment. A greater sense of control was recorded in patients with history of MF lasting 7–10 years in contrast to those living with the disease for 4–6 years (p=0.046). This study in MF patients indicates variables which may be able to predict one's perception of the illness. This information may be beneficial in planning future supportive interventions for this patient population. [ABSTRACT FROM AUTHOR]

The incidence of primary cutaneous B-cell lymphomas (PCBCL) in the pediatric population is unknown, and the information on pediatric PCBCL has mostly been gathered from individual case reports or series from single centers. To assess the incidence of PCBCL in the pediatric population (<20 years) compared with adult patients (≥20 years) and delineate its demographic and clinicopathologic characteristics. This was a population-based, retrospective cohort study of patients in 18 cancer registries in the United States diagnosed between 2000 to 2016 through the Surveillance, Epidemiology, and End Results (SEER) program. Age-adjusted incidence rates were calculated for PCBCL in pediatric and adult populations. Demographic, clinical, and pathological characteristics were compared between the two groups. 5,128 adult and 48 pediatric PCBCL cases were included. The median age at diagnosis in the pediatric group was 16.5 years. The major histologic subtypes of pediatric cases were marginal zone lymphoma (77.1%), diffuse large B-cell lymphoma (12.5%) and follicle center lymphoma (10.4%), which significantly differed from the distribution in the adult group (p<0.001) where subtypes were equally distributed. The age-adjusted pediatric PCBCL incidence rate (per 1,000,000 person‐years) was 0.12 (95% CI 0.09-0.16) and incidence in the adult population was approximately 40-fold higher (IRR 41.4, 95% CI 31.2-56.2, P<0.001). All 48 pediatric cases were alive during a median follow-up time of 48 months. Pediatric PCBCL is a rare and indolent disease, which affects mostly adolescents of both sexes. Clinical presentation is similar to adults, but marginal zone subtype is significantly over-represented. [ABSTRACT FROM AUTHOR]