1. Radiotherapy in cutaneous lymphomas: Recommendations from the EORTC cutaneous lymphoma tumour group.
- Author
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Elsayad, Khaled, Guenova, Emmanuella, Assaf, Chalid, Nicolay, Jan P., Trautinger, Franz, Stadler, Rudolf, Waldstein, Cora, Boterberg, Tom, Meijnders, Paul, Kirova, Youlia, Dobos, Gabor, Duque-Santana, Victor, Riggenbach, Elena, Elsheshtawy, Wael, Niezink, Anne, Papadavid, Evangelia, Scarisbrick, Julia, Vermeer, Maarten, Neelis, Karen J., and Bagot, Martine
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MEDICAL protocols , *RADIOTHERAPY , *CANCER patients , *ONCOLOGY , *DECISION making in clinical medicine , *CUTANEOUS T-cell lymphoma , *OVERTREATMENT , *MEDICAL radiology , *QUALITY of life , *RADIATION doses , *ONCOLOGISTS - Abstract
The number of primary cutaneous lymphoma patients receiving low-dose radiotherapy is increasing, though controlled clinical trials defining the standard radiation dose for each specific entity have not yet been completed. Radiation oncologists are left with making highly individualized decisions that would be better enriched by additional clinical evidence. In this expert opinion, we aim to provide a clear recommendation to improve the current practice of radiation oncology. In addition, existing literature has been reviewed to develop recommendations for all types of primary cutaneous lymphoma. A prospective trial is urgently needed to identify the factors influencing patient outcomes following different radiation doses. • Reduced-dose RT is highly effective for patients with indolent types. • RT enhances the QoL in many patients with primary cutaneous lymphoma. • Radiation doses for primary cutaneous DLBCL range between 16 to 40 Gy. • There is still room for improvement in treating patients with cutaneous lymphoma. • The EORTC-CLTG provides radiotherapy dose recommendations to avoid overtreatment. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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