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Introduction: FNAC has a pivotal role in the evaluation of breast lesions. Cytological grading systems are being utilized for the categorization of breast lesions. Modified Masood’s scoring System (MMSS) is used to improve the grading system for accurate pre-operative diagnosis. This study aims to assess the effectiveness and accuracy of the Modified Masood Scoring System for evaluating breast lesions and their correlation with histopathological diagnosis. Materials and Methods: This is a prospective study conducted in the Department of Pathology, MGM Medical College, Navi Mumbai which included 40 patients who presented with clinically palpable breast lump and were subjected to FNAC along with histopathological examination. The cytological smears were grouped into four categories according to MMSS. Correlation and concordance analysis between cytological categories and histopathological diagnosis was carried out. Observations and Results: The age of the patients ranged from 17 to 70 years with a mean age of 38.12 years, right-sided breast lesions were more common as compared to the left side. Of the total 40 cases, 27 cases were benign, and 13 cases were malignant on histopathology. The most common benign breast lesion was Fibroadenoma [Figure 1] and the malignant lesion was infiltrating duct carcinoma [Figure 2]. The sensitivity, specificity, Positive predictive value, Negative predictive value, and diagnostic accuracy were 76.9%, 100%, 100%, 90%, and 92.5% respectively. Conclusion: MMSS is simple, cost-effective, easily reproducible, reliable, and can be applied to FNAC aspirates to increase the diagnostic accuracy of Breast Lesions. [ABSTRACT FROM AUTHOR]

Introduction: Tuberculosis (TB) is the most prevalent infectious disease which is brought by the mycobacterium tuberculosis. In addition to the lung tissue, TB also affects the bone marrow. Significant haematological and coagulation abnormalities are associated with TB. Therefore the diagnosis, prognosis, and therapeutic response can also be indicated by these haematological and coagulation markers. These coagulation abnormalities can lead to stroke and DIC leading to increased mortality. Aims To evaluate the haematological and coagulation parameters in pulmonary tuberculosis patients. Methods and Materials: In this study a total of 50 patients with confirmed tuberculosis were chosen using purposive sampling. Four millilitres of venous blood were drawn while taking the necessary aseptic precaution. Sysmex XN 1000 6-part haematology analyser was used to perform hematologicalanalysis on two millilitres of ethylenediamine tetra acetic acid (EDTA)vacutainer tubes. Rest two millilitres of blood in sodium citrate vacutainer tube was used to perform coagulation parameters analysis on ACL elite pro coagulation analyser for measurement of D dimer and fibrinogen. Results Hemoglobin and other blood indices were marginally lower in both sexes compared to healthy controls. Patients with tuberculosis show significantly greater levels of white blood cells (WBC), platelets, D-dimer, and fibrinogen when compared to healthy controls. P-value < 0.05 indicated that these increases were statistically significant. [ABSTRACT FROM AUTHOR]