15 results on '"Emmanuel Andrès"'
Search Results
2. Hearing Loss and Sixth Cranial Nerve Paresis after COVID-19
- Author
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Noel Lorenzo Villalba, Léa Pierre, Javier Guerrero-Niño, Xavier Jannot, and Emmanuel Andrès
- Subjects
sixth nerve paresis ,auditory acuity ,mri ,Medicine - Abstract
An 80-year-old patient was admitted to the internal medicine department for binocular diplopia and hearing loss with sudden onset. The patient had presented with SARS-CoV-2 infection 3 weeks previously and had been admitted to hospital. Complete work-up including autoimmunity, serum and LCR viral serology and MRI did not allow a diagnosis to be established. The hypothesis of a microvascular origin or the previous SARS-CoV-2 infection was considered. The latter was retained in light of the temporal relationship, the absence of other pathologies after exhaustive work-up, and the clinical evolution.
- Published
- 2022
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3. First Test of an Automated Detection Platform to Identify Risk of Decompensation in Elderly Patients
- Author
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Abrar-Ahmad Zulfiqar, Orianne Vaudelle, Mohamed Hajjam, Dominique Letourneau, Jawad Hajjam, Sylvie Ervé, Anna Karen Garate Escamilla, Amir Hajjam, and Emmanuel Andrès
- Subjects
telemonitoring ,geriatric risks ,mypredi ,e-platform ,ger-e-tec study ,Medicine - Abstract
Introduction: We tested the MyPrediTM e-platform which is dedicated to the automated, intelligent detection of situations posing a risk of decompensation in geriatric patients. Objective: The goal was to validate the technological choices, to consolidate the system and to test the robustness of the MyPrediTM e-platform through daily use. Results: The telemedicine solution took 3,552 measurements for a hospitalized patient during her stay, with an average of 237 measurements per day, and issued 32 alerts, with an average of 2 alerts per day. The main risk was heart failure which generated the most alerts (n=13). The platform had 100% sensitivity for all geriatric risks, and had very satisfactory positive and negative predictive values. Conclusion: The present experiment validates the technological choices, the tools and the solutions developed.
- Published
- 2020
- Full Text
- View/download PDF
4. Cutaneous Complications Secondary to Haemostasis Abnormalities in COVID-19 Infection
- Author
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Noel Lorenzo-Villalba, Yasmine Maouche, Aneska Syrovatkova, Felix Pham, Jean-Baptiste Chahbazian, Pierre Pertoldi, Emmanuel Andrès, and Abrar-Ahmad Zulfiqar
- Subjects
covid-19 ,dissecting haematoma ,dermatoporosis ,coagulation abnormalities ,Medicine - Abstract
We describe the case of a patient hospitalized for acute decompensated heart failure in a standard medical ward. During hospitalization, he was diagnosed with COVID-19 and transferred to a special unit. The clinical course was marked by worsening of the respiratory disease, the development of right parotiditis and thrombosis of the left internal jugular vein. Therapeutic anticoagulation was initiated and 2 days later, the minimal dermatoporosis lesions previously present in the upper extremities evolved to haemorrhagic bullae with intra-bullae blood clots and dissecting haematomas. Surgical management of the dissecting haematomas was difficult in the context of haemostasis abnormalities. The patient died 29 days after hospital admission.
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- 2020
- Full Text
- View/download PDF
5. First Test of an Automated Detection Platform to Identify Risk of Decompensation in Elderly Patients
- Author
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Orianne Vaudelle, Mohamed Hajjam, Emmanuel Andrès, Sylvie Ervé, Amir Hajjam, Jawad Hajjam, Dominique Letourneau, Abrar-Ahmad Zulfiqar, and Anna Karen Garate Escamilla
- Subjects
Telemedicine ,2019-20 coronavirus outbreak ,020205 medical informatics ,Coronavirus disease 2019 (COVID-19) ,Hospitalized patients ,ger-e-tec study ,lcsh:Medicine ,02 engineering and technology ,03 medical and health sciences ,0302 clinical medicine ,Robustness (computer science) ,Positive predicative value ,0202 electrical engineering, electronic engineering, information engineering ,Internal Medicine ,Medicine ,Decompensation ,Elderly patient ,e-platform ,mypredi ,business.industry ,lcsh:R ,telemonitoring ,Articles ,medicine.disease ,geriatric risks ,030220 oncology & carcinogenesis ,Medical emergency ,business - Abstract
INTRODUCTION: We tested the MyPredi(™) e-platform which is dedicated to the automated, intelligent detection of situations posing a risk of decompensation in geriatric patients. OBJECTIVE: The goal was to validate the technological choices, to consolidate the system and to test the robustness of the MyPredi(™) e-platform through daily use. RESULTS: The telemedicine solution took 3,552 measurements for a hospitalized patient during her stay, with an average of 237 measurements per day, and issued 32 alerts, with an average of 2 alerts per day. The main risk was heart failure which generated the most alerts (n=13). The platform had 100% sensitivity for all geriatric risks, and had very satisfactory positive and negative predictive values. CONCLUSION: The present experiment validates the technological choices, the tools and the solutions developed. LEARNING POINTS: Patients with chronic conditions can be monitored with telemedicine systems to optimise their management, particularly during the COVID-19 pandemic. The goal was to validate the technological choices, to consolidate the system and to test the robustness of the MyPredi(™) e-platform, through daily use in an elderly patient. The present experiment demonstrates the relevance of the technological choices, the tools and the solutions developed.
- Published
- 2020
6. Cutaneous Complications Secondary to Haemostasis Abnormalities in COVID-19 Infection
- Author
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Emmanuel Andrès, Abrar-Ahmad Zulfiqar, Jean-Baptiste Chahbazian, Noel Lorenzo-Villalba, Yasmine Maouche, Aneska Syrovatkova, Felix Pham, and Pierre Pertoldi
- Subjects
medicine.medical_specialty ,Acute decompensated heart failure ,Coronavirus disease 2019 (COVID-19) ,lcsh:Medicine ,Context (language use) ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Internal Medicine ,medicine ,030212 general & internal medicine ,Lupus anticoagulant ,Left internal jugular vein ,business.industry ,lcsh:R ,Respiratory disease ,Articles ,medicine.disease ,Thrombosis ,Surgery ,Discontinuation ,dissecting haematoma ,covid-19 ,dermatoporosis ,coagulation abnormalities ,business - Abstract
We describe the case of a patient hospitalized for acute decompensated heart failure in a standard medical ward. During hospitalization, he was diagnosed with COVID-19 and transferred to a special unit. The clinical course was marked by worsening of the respiratory disease, the development of right parotiditis and thrombosis of the left internal jugular vein. Therapeutic anticoagulation was initiated and 2 days later, the minimal dermatoporosis lesions previously present in the upper extremities evolved to haemorrhagic bullae with intra-bullae blood clots and dissecting haematomas. Surgical management of the dissecting haematomas was difficult in the context of haemostasis abnormalities. The patient died 29 days after hospital admission. LEARNING POINTS Single room accommodation should be preferred to double room accommodation in standard wards during the COVID-19 pandemic. Anticoagulation therapy and the presence of lupus anticoagulant may induce cutaneous complications during COVID-19 infection. The discontinuation of anticoagulation therapy did not help improve the management of cutaneous lesions.
- Published
- 2020
7. Thrombocytopenia in the Course of COVID-19 Infection
- Author
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Emmanuel Andrès, Marc Auburtin, Yasmine Maouche, Olivier Keller, Abrar-Ahmad Zulfiqar, Noel Lorenzo-Villalba, Alain Meyer, and Marie Helene Schuhmacher
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,immunoglobulins ,Eltrombopag ,lcsh:Medicine ,thrombocytopenia ,Gastroenterology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,hemic and lymphatic diseases ,Internal medicine ,Internal Medicine ,medicine ,Platelet ,Mucosal bleeding ,biology ,business.industry ,lcsh:R ,COVID-19 ,Articles ,Immune thrombocytopenia ,Severe thrombocytopenia ,Purpura ,030104 developmental biology ,immune thrombocytopenia ,chemistry ,030220 oncology & carcinogenesis ,biology.protein ,medicine.symptom ,Antibody ,eltrombopag ,business - Abstract
We report three cases of severe thrombocytopenia during COVID-19 infection associated with either cutaneous purpura or mucosal bleeding. The initial investigations ruled out other causes of thrombocytopenia. Two of the patients were treated with intravenous immunoglobulins and eltrombopag, while the third recovered spontaneously. A good clinical and biological response was achieved in all patients leading to hospital discharge. LEARNING POINTS Immune thrombocytopenia should be considered in COVID-19-infected patients presenting with thrombocytopenia. Coronavirus-related thrombocytopenia can be severe and life-threatening. Despite the severity of coronavirus-related immune thrombocytopenia, recovery may be spontaneous or achieved following immunoglobulin or platelet growth factor administration.
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- 2020
8. Anosmia and Dysgeusia in the Absence of Other Respiratory Diseases: Should COVID-19 Infection Be Considered?
- Author
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Yasmine Maouche, Aneska Syrovatkova, Jean Baptiste Chahbazian, Maria Belen Alonso Ortiz, Abrar-Ahmad Zulfiqar, Pierre Pertoldi, Zaida Cordoba Sosa, Noel Lorenzo Villalba, and Emmanuel Andrès
- Subjects
medicine.medical_specialty ,Pediatrics ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Anosmia ,lcsh:Medicine ,Context (language use) ,03 medical and health sciences ,0302 clinical medicine ,Epidemiology ,Internal Medicine ,medicine ,030212 general & internal medicine ,Respiratory system ,SARS-CoV-2 ,business.industry ,lcsh:R ,COVID-19 ,Articles ,humanities ,Dysgeusia ,2019-nCoV ,dysgeusia ,medicine.symptom ,business ,anosmia ,030217 neurology & neurosurgery - Abstract
We describe two elderly patients evaluated at emergency departments for anosmia/dysgeusia in the absence of any other respiratory symptoms prior to or upon admission. In the current epidemiological context, clinical and biological work-up led to a diagnosis of COVID-19 infection. Unfortunately, one of the patients died during hospitalization, but the other recovered and was discharged. LEARNING POINTS In the current epidemiological situation, anosmia and dysgeusia in the absence of other respiratory conditions should be carefully evaluated. Special attention should be given to patients with non-classic COVID-19 symptoms in order to reduce transmission and protect health providers
- Published
- 2020
9. Idiopathic CD4+ T-cell Lymphocytopenia: Report of a Case 11 Years after Diagnosis
- Author
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Noel Lorenzo Villalba, Zaida Cordoba Sosa, Yasmine Maouche, Emmanuel Andrès, Maria Belen Alonso Ortiz, and Abrar-Ahmad Zulfiqar
- Subjects
medicine.medical_specialty ,Cd4 t cell ,medicine.diagnostic_test ,business.industry ,lcsh:R ,Lymphocyte Immunophenotyping ,Human immunodeficiency virus (HIV) ,lcsh:Medicine ,hiv ,lymphocyte immunophenotyping ,Physical examination ,Articles ,medicine.disease ,medicine.disease_cause ,Dermatology ,Asymptomatic ,lymphocytopenia ,Internal Medicine ,medicine ,Lymphocytopenia ,medicine.symptom ,business - Abstract
We report the case of a 23-year-old woman evaluated for asthenia and lymphocytopenia. Clinical examination was unremarkable but laboratory tests showed the presence of CD4 lymphocytopenia. Secondary causes of CD4 lymphocytopenia were ruled out and a previous diagnosis of idiopathic CD4+ T-cell lymphocytopenia was retained. CD4 lymphocytopenia has persisted for 11 years now but the patient has been clinically asymptomatic. LEARNING POINTS CD4+ T-cell lymphocytopenia needs to be meticulously evaluated and secondary causes ruled out. The patient has been clinically asymptomatic for 11 years. Measurement of CD4 subsets twice yearly seems to be appropriate.
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- 2020
10. Symptomatic postoperative compressive pneumocephalus after cholecystectomy
- Author
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Zaky Mehdi Benamar, Camille Huet, Maxime Rousseau, Léa Docquier, Emmanuel Andres, Pascal Bilbaut, and Noel Lorenzo-Villalba
- Subjects
pneumocephalus ,cerebral ct scan ,cholescystectomy ,Medicine - Abstract
A 75-year-old woman with a history of chronic hydrocephalus due to stenosis of the aqueduct of Sylvius was examined at the emergency department for altered mental status. There was placement of a ventriculoperitoneal shunt in 1970 complicated by meningitis, leading to removal of the material and ventriculociternostomy as definitive treatment in 2004. About one month previously, she had undergone a laparoscopic cholecystectomy complicated by an intra-abdominal collection. Clinical examination at the emergency department revealed a Glasgow score of 8 (E3 V1 M4). In the emergency department the patient presented a tonic-clonic seizure before a cerebral CT scan was performed showing a massive compressive pneumocephalus, then a second seizure. The patient was finally admitted to the neurosurgery department and underwent surgery.
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- 2023
- Full Text
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11. Focal myositis of the sternocleidomastoid muscle: a rare and uncommon cause of cervical mass
- Author
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Léa Docquier, Xavier Jannot, Zaida Córdoba-Sosa, Léa Pierre, Pierre Alexis Austrusseau, Emmanuel Andres, and Noel Lorenzo Villalba
- Subjects
neck masses ,sternocleidomastoid muscle ,magnetic resonance image (mri) ,Medicine - Abstract
We report on a 70-year-old male patient admitted to the internal medicine department for evaluation of a right cervical mass. He had been treated with antibiotics as an outpatient by his primary care doctor. Upon admission the patient was asymptomatic, but within a few hours his cervical mass enlarged; this enlargement was confined to the right sternocleidomastoid muscle. Complete blood investigations including serology and autoimmunity were negative. The neck scan and MRI were in favour of myositis. No other lesions were found either in the nasal fibre-optic exam or in the thoracic-abdominal-pelvic scan. The biopsy of the muscle showed a lymphoplasmacytic inflammatory infiltrate of the perimysium. The diagnosis of focal myositis was made. The patient clinically improved during hospitalisation with complete resolution of symptoms without any specific intervention.
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- 2023
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12. Recurrent Episodes of Hypokalaemia during Treatment with Inhaled Beta-2 Agonist Revealing Gitelman Syndrome, an Uncommon Clinical Entity
- Author
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Nery Sablón-González, Yanet Parodis-Lopez, Maria Belen Alonso-Ortiz, Angélica Laurin, Emmanuel Andres, and Noel Lorenzo Villalba
- Subjects
hypokalemia ,metabolic alcalosis ,gitelman syndrome ,Medicine - Abstract
A 28-year-old female patient was hospitalized for mild–moderate hypokalaemia which was persistent despite discontinuation of beta-2 agonist bronchodilator treatment. Her past medical history was relevant for two episodes of severe hypokalaemia after active inhaled beta-2 agonist treatment for asthma crisis. Investigations revealed increased potassium in spot urine with a transtubular potassium gradient
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- 2022
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13. Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
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Noel Lorenzo Villalba, Emmanuel Andrés, and Alain Meyer
- Subjects
Medicine - Abstract
We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenous immunoglobulin was added. One year after initial treatment was started, as levels of creatine kinase (CK) were >1000 U/l, treatment with rituximab was added. Despite a 3-year delay before treatment, muscle strength improved even though CK levels remain elevated.
- Published
- 2021
- Full Text
- View/download PDF
14. Thrombocytopenia in the Course of COVID-19 Infection
- Author
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Noel Lorenzo-Villalba, Abrar-Ahmad Zulfiqar, Marc Auburtin, Marie Helene Schuhmacher, Alain Meyer, Yasmine Maouche, Olivier Keller, and Emmanuel Andres
- Subjects
covid-19 ,thrombocytopenia ,immune thrombocytopenia ,immunoglobulins ,eltrombopag ,Medicine - Abstract
We report three cases of severe thrombocytopenia during COVID-19 infection associated with either cutaneous purpura or mucosal bleeding. The initial investigations ruled out other causes of thrombocytopenia. Two of the patients were treated with intravenous immunoglobulins and eltrombopag, while the third recovered spontaneously. A good clinical and biological response was achieved in all patients leading to hospital discharge.
- Published
- 2020
- Full Text
- View/download PDF
15. Anosmia and Dysgeusia in the Absence of Other Respiratory Diseases: Should COVID-19 Infection Be Considered?
- Author
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Noel Lorenzo Villalba, Yasmine Maouche, Maria Belen Alonso Ortiz, Zaida Cordoba Sosa, Jean Baptiste Chahbazian, Aneska Syrovatkova, Pierre Pertoldi, Emmanuel Andres, and Abrar-Ahmad Zulfiqar
- Subjects
covid-19 ,sars-cov-2 ,2019-ncov ,anosmia ,dysgeusia ,Medicine - Abstract
We describe two elderly patients evaluated at emergency departments for anosmia/dysgeusia in the absence of any other respiratory symptoms prior to or upon admission. In the current epidemiological context, clinical and biological work-up led to a diagnosis of COVID-19 infection. Unfortunately, one of the patients died during hospitalization, but the other recovered and was discharged.
- Published
- 2020
- Full Text
- View/download PDF
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