1. Seroprevalence of hepatitis E virus in Argentinean blood donors
- Author
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Federico A. Di Lello, Sandra Gallego, Fabiana Vargas, Sonia Bartoli, Roberto Fernández, Diego Martin Flichman, Rosángela Ruiz, Sebastián Blanco, Claudio Galli, Alfredo P. Martínez, Adriana Alter, Luis Horacio Carrizo, and Jorgelina L. Blejer
- Subjects
medicine.medical_specialty ,viruses ,Blood Donors ,medicine.disease_cause ,Virus ,Hepatitis E virus ,Seroepidemiologic Studies ,Epidemiology ,Medicine ,Seroprevalence ,Humans ,Hepatitis Antibodies ,Aged ,Hepatology ,biology ,business.industry ,Significant difference ,Gastroenterology ,virus diseases ,medicine.disease ,digestive system diseases ,Hepatitis E ,Immunoglobulin M ,Immunology ,biology.protein ,RNA, Viral ,business ,Viral hepatitis - Abstract
BACKGROUND Hepatitis E virus (HEV) is the main cause of enteric acute viral hepatitis worldwide. In this epidemiological framework, it has become a threat to blood safety and a relevant issue for blood transfusions. However, there is a paucity of data regarding prevalence of HEV infection. The aim of this study was to determine HEV seroprevalence in blood donors from different regions from Argentina. MATERIAL AND METHODS Serum samples from 391 individuals attending five blood donor centers located in different regions from Argentina were analyzed for anti-HEV IgG and anti-HEV IgM. RESULTS Overall, anti-HEV IgG was detected in 44 out of 391 (11.3%) samples. HEV prevalence ranged from 5.1 to 20.0% among different country regions. A significant difference in blood donors' age was observed between anti-HEV IgG positive and negative individuals [44 (37-51) vs. 35 (27-43), P
- Published
- 2020