Cotter, Gad, Davison, Beth A., Adams, Kirkwood F., Ambrosy, Andrew P., Atabaeva, Lina, Beavers, Craig J., Bhatt, Ankeet S., Givertz, Michael M., Grodin, Justin L., Lala, Anuradha, Novosadov, Mikhail, Sokos, George G., Takagi, Koji, Teerlink, John R., and Bhatt, Deepak L.
Acute heart failure (AHF) is a common cause of hospitalization, particularly among older individuals, and has high mortality and readmission rates. Adherence to guideline-directed medical therapy (GDMT) is crucial for improving outcomes in heart failure (HF) patients, as non-adherence can lead to exacerbations and adverse outcomes. However, studies have shown that medication non-adherence rates among HF patients can be as high as 70%. Various factors contribute to non-adherence, including patient circumstances, treatment-related factors, and healthcare system and payer factors. Adherence interventions, such as patient education, medication regimen management, and reminders, have been shown to improve medication adherence and reduce mortality and hospital readmissions in HF patients. Improving adherence to GDMT is essential for improving AHF outcomes, and further research is needed to identify effective approaches to enhance medication adherence. [Extracted from the article]