1. Co-occurrence of anxiety and depressive symptoms following breast cancer surgery and its impact on quality of life
- Author
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Christine Miaskowski, Marshall Gold, Steven M. Paul, Laura B. Dunn, Bethany J. Phoenix, Deborah Hamolsky, and Jon D. Levine
- Subjects
Subsyndromal depression ,Disease ,Anxiety ,Breast cancer ,0302 clinical medicine ,7.1 Individual care needs ,Quality of life ,Surveys and Questionnaires ,80 and over ,030212 general & internal medicine ,Adjuvant ,Mastectomy ,Depression (differential diagnoses) ,Cancer ,Aged, 80 and over ,Depression ,Oncology (nursing) ,Age Factors ,General Medicine ,Middle Aged ,Anxiety Disorders ,Mental Health ,Chemotherapy, Adjuvant ,030220 oncology & carcinogenesis ,Female ,medicine.symptom ,Clinical psychology ,Adult ,medicine.medical_specialty ,Patients ,Oncology and Carcinogenesis ,Breast Neoplasms ,Nursing ,Article ,7.3 Management and decision making ,03 medical and health sciences ,Clinical Research ,Behavioral and Social Science ,medicine ,Chi-square test ,Humans ,Chemotherapy ,Aged ,Performance status ,business.industry ,Life satisfaction ,medicine.disease ,Surgery ,Quality of Life ,Management of diseases and conditions ,business ,Mind and Body - Abstract
Purpose Little is known about the prevalence of combined anxiety and depressive symptoms (CADS) in breast cancer patients. Purpose was to evaluate for differences in demographic and clinical characteristics and quality of life (QOL) prior to breast cancer surgery among women classified into one of four distinct anxiety and/or depressive symptom groups. Methods A total of 335 patients completed measures of anxiety and depressive symptoms and QOL prior to and for 6 months following breast cancer surgery. Growth Mixture Modelling (GMM) was used to identify subgroups of women with distinct trajectories of anxiety and depressive symptoms. These results were used to create four distinct anxiety and/or depressive symptom groups. Differences in demographic, clinical, and symptom characteristics, among these groups were evaluated using analyses of variance and Chi square analyses. Results A total of 44.5% of patients were categorized with CADS. Women with CADS were younger, non-white, had lower performance status, received neoadjuvant or adjuvant chemotherapy, had greater difficulty dealing with their disease and treatment, and reported less support from others to meet their needs. These women had lower physical, psychological, social well-being, and total QOL scores. Higher levels of anxiety with or without subsyndromal depressive symptoms were associated with increased fears of recurrence, hopelessness, uncertainty, loss of control, and a decrease in life satisfaction. Conclusions Findings suggest that CADS occurs in a high percentage of women following breast cancer surgery and results in a poorer QOL. Assessments of anxiety and depressive symptoms are warranted prior to surgery for breast cancer.
- Published
- 2016