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Start Over Author "Junhao Jia" Journal european journal of organic chemistry
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2. Asymmetric Synthesis of Concentricolide

Author

Xiaojing Liu, Lingling Hu, Di Zhang, Junhao Jia, Xiaochuan Chen, and Lizhen Jiang

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Concentricolide, Stereochemistry, Organic Chemistry, Condensation, Enantioselective synthesis, Oxazoline, Physical and Theoretical Chemistry, Aldehyde, Combinatorial chemistry, Salicylic acid
Abstract

A practical strategy for the synthesis of both (–)- and (+)-concentricolide from salicylic acid has been developed. The key feature of the approach is sequential aromatic lithiation and condensation with an aldehyde directed by a chiral oxazoline unit derived either from L- or D-phenylalaninol, which is employed as an auxiliary.

Published
2015
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