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Start Over Author "Dinia, L." Journal european journal of radiology
2 results on '"Dinia, L."'

1. Predictors of response to endovascular treatment of posterior circulation stroke

Author

Marc Ribo, Pilar Coscojuela, Manuel Requena, Carla Vert, Carlos A. Molina, Alex Rovira, Marta Rubiera, David Uriarte Hernández, Laura Ludovica Gramegna, Alejandro Tomasello, Fernando Melendez, Lavinia Dinia, Manuel Quintana, and Gramegna LL, Requena M, Dinia L, Melendez F, Hernández D, Coscojuela P, Quintana M, Vert C, Rubiera M, Ribò M, Rovira À, Molina C, Tomasello A.

Subjects
Male, medicine.medical_specialty, Multivariate analysis, Population, Neuroimaging, Logistic regression, Brain Ischemia, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Odds Ratio, medicine, Humans, Thrombolytic Therapy, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Endovascular treatment, education, Stroke, Aged, Retrospective Studies, Thrombectomy, Aged, 80 and over, Univariate analysis, education.field_of_study, business.industry, Endovascular Procedures, General Medicine, Middle Aged, Intracranial Arteriosclerosis, medicine.disease, Posterior circulation strokeEndovascular treatmentIntracranial atherosclerosis, Cerebral Angiography, Stenosis, Logistic Models, Treatment Outcome, 030220 oncology & carcinogenesis, Cardiology, Female, Intracranial Atherosclerosis, business
Abstract

BACKGROUND: Endovascular treatment is considered a reasonable approach for patients with acute posterior circulation stroke, but it remains uncertain which patients will benefit the most from it. OBJECTIVE: To find independent clinical and angiographic predictors of outcome after endovascular treatment for posterior circulation stroke. METHODS: We evaluated consecutive patients with acute posterior circulation stroke who underwent endovascular treatment in our comprehensive stroke center from January 2015 to December 2017. Good outcome was defined as a modified Rankin score of 0-3 at 90 days. Intracranial atheromatous disease was established on focal stenosis recorded during endovascular treatment. Associations were sought between a good outcome and clinical and angiographic factors. Adjusted logistic regression models were used to define independent outcome predictors. RESULTS: Forty-seven consecutive patients were included: mean age 70.9 ± 12.1 years, median admission NIHSS score, 16 (IQR: 8-30). On univariate analysis, age (p = 0.01), smoking (p = 0.04), hypertension (p = 0.03), successful reperfusion (p = 0.04), presence of extracranial atherosclerosis (p = 0.02), and absence of atherosclerosis (p = 0.03) were significantly associated with a good outcome. On multivariate analysis, age

Published
2019

2. Predictors of response to endovascular treatment of posterior circulation stroke.

Author

Gramegna LL, Requena M, Dinia L, Melendez F, Hernández D, Coscojuela P, Quintana M, Vert C, Rubiera M, Ribò M, Rovira À, Molina C, and Tomasello A

Subjects
Aged, Aged, 80 and over, Brain Ischemia diagnostic imaging, Brain Ischemia physiopathology, Cerebral Angiography methods, Female, Humans, Intracranial Arteriosclerosis diagnostic imaging, Intracranial Arteriosclerosis physiopathology, Intracranial Arteriosclerosis therapy, Logistic Models, Male, Middle Aged, Neuroimaging methods, Odds Ratio, Retrospective Studies, Stroke diagnostic imaging, Stroke physiopathology, Thrombectomy methods, Thrombolytic Therapy methods, Treatment Outcome, Brain Ischemia therapy, Endovascular Procedures methods, Stroke therapy
Abstract

Background: Endovascular treatment is considered a reasonable approach for patients with acute posterior circulation stroke, but it remains uncertain which patients will benefit the most from it., Objective: To find independent clinical and angiographic predictors of outcome after endovascular treatment for posterior circulation stroke., Methods: We evaluated consecutive patients with acute posterior circulation stroke who underwent endovascular treatment in our comprehensive stroke center from January 2015 to December 2017. Good outcome was defined as a modified Rankin score of 0-3 at 90 days. Intracranial atheromatous disease was established on focal stenosis recorded during endovascular treatment. Associations were sought between a good outcome and clinical and angiographic factors. Adjusted logistic regression models were used to define independent outcome predictors., Results: Forty-seven consecutive patients were included: mean age 70.9 ± 12.1 years, median admission NIHSS score, 16 (IQR: 8-30). On univariate analysis, age (p = 0.01), smoking (p = 0.04), hypertension (p = 0.03), successful reperfusion (p = 0.04), presence of extracranial atherosclerosis (p = 0.02), and absence of atherosclerosis (p = 0.03) were significantly associated with a good outcome. On multivariate analysis, age <70 years (odds ratio = 6.20, 95%CI 1.52-25.47, p = 0.01) and absence of intracranial atherosclerosis (odds ratio = 6.45, 95% CI 1.09-38.24, p = 0.04) were independently associated with a good outcome., Conclusions: Pretreatment determination of the presence or absence of intracranial atherosclerosis can aid management of posterior circulation stroke patients. The absence of intracranial atherosclerosis may have value as a positive selection criterion for endovascular treatment in future trials. The presence of intracranial atherosclerosis could be used as a selection tool in future studies investigating new treatment protocols for this population., (Copyright © 2019. Published by Elsevier B.V.)

Published
2019
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