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Objectives: Patients with cystic fibrosis (CF) increasingly require imaging for the diagnosis of abdominal complications. We prospectively evaluated the image quality and signal-to-noise ratio (SNR) of a modern radial volumetric encoding (RAVE) T2/T1 hybrid sequence for abdominal magnetic resonance imaging (MRI). RAVET2/T1 is a three-dimensional radial sequence with fat saturation and blood flow suppression that acquires T2- and T1-weighted contrasts in one scan in an identical slice position during free-breathing.Methods: Sixteen CF patients underwent axial T2 HASTE (1000 ms/93 ms TR/TE), T1 DIXON (6.8 ms/2.4 ms/4.8 ms TR/TE1/TE2), and RAVE T2/T1 hybrid sequence (1200 ms/1.7 ms/3.3 ms/4.9 ms/102 ms TR/TE1/TE2/TE3/TE4) of the upper abdomen at 1.5 Tesla. The SNR values in six different regions were assessed and compared using the Wilcoxon signed-rank test. The image quality criteria were rated on a 5-point Likert scale.Results: In all regions, the SNR was significantly higher in the T2 weighted aspect of the RAVE T2/T1 hybrid sequence compared to T2 HASTE (p < 0.05) and significantly lower in the T1 weighted in-phase aspect of the RAVE T2/T1 hybrid sequence compared to the T1 DIXON sequence (p < 0.05). Qualitatively the T2 weighted aspect of the RAVE T2/T1 hybrid sequence was rated significantly higher than the T2 HASTE in 6 of 7 categories (p < 0.05) and the T1 weighted in-phase aspect of the RAVE T2/T1 hybrid sequence was rated significantly higher than the T1 DIXON in 2 of 6 categories (p < 0.05).Conclusions: The abdominal radial RAVE T2/T1 hybrid sequence provided higher image quality and SNR than the T2HASTEsequence. Together with increased robustness against motion artifacts, the RAVE T2/T1 hybrid sequence appears to be a good tool for abdominal imaging in CF patients. [ABSTRACT FROM AUTHOR]

Objectives: Patients with cystic fibrosis (CF) increasingly require imaging for the diagnosis of abdominal complications. We prospectively evaluated the image quality and signal-to-noise ratio (SNR) of a modern radial volumetric encoding (RAVE) T 2 /T 1 hybrid sequence for abdominal magnetic resonance imaging (MRI). RAVET 2 /T 1 is a three-dimensional radial sequence with fat saturation and blood flow suppression that acquires T 2 - and T 1 -weighted contrasts in one scan in an identical slice position during free-breathing., Methods: Sixteen CF patients underwent axial T 2 HASTE (1000 ms/93 ms TR/TE), T 1 DIXON (6.8 ms/2.4 ms/4.8 ms TR/TE 1 /TE 2 ), and RAVE T 2 /T 1 hybrid sequence (1200 ms/1.7 ms/3.3 ms/4.9 ms/102 ms TR/TE 1 /TE 2 /TE 3 /TE 4 ) of the upper abdomen at 1.5 Tesla. The SNR values in six different regions were assessed and compared using the Wilcoxon signed-rank test. The image quality criteria were rated on a 5-point Likert scale., Results: In all regions, the SNR was significantly higher in the T 2 weighted aspect of the RAVE T 2 /T 1 hybrid sequence compared to T 2 HASTE (p < 0.05) and significantly lower in the T 1 weighted in-phase aspect of the RAVE T 2 /T 1 hybrid sequence compared to the T 1 DIXON sequence (p < 0.05). Qualitatively the T 2 weighted aspect of the RAVE T 2 /T 1 hybrid sequence was rated significantly higher than the T 2 HASTE in 6 of 7 categories (p < 0.05) and the T 1 weighted in-phase aspect of the RAVE T 2 /T 1 hybrid sequence was rated significantly higher than the T 1 DIXON in 2 of 6 categories (p < 0.05)., Conclusions: The abdominal radial RAVE T 2 /T 1 hybrid sequence provided higher image quality and SNR than the T 2 HASTEsequence. Together with increased robustness against motion artifacts, the RAVE T 2 /T 1 hybrid sequence appears to be a good tool for abdominal imaging in CF patients., (Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.)