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Your search keyword '"Takayoshi Shimohata"' showing total 7 results
Start Over Author "Takayoshi Shimohata" Journal european neurology
7 results on '"Takayoshi Shimohata"'

1. Nutritional Status and Changes in Body Weight in Patients with Multiple System Atrophy

Author

Tomoe Sato, Maho Shiobara, Takayoshi Shimohata, and Masatoyo Nishizawa

Subjects
Male, 0301 basic medicine, medicine.medical_specialty, Activities of daily living, Serum albumin, Nutritional Status, Body weight, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Atrophy, Internal medicine, Activities of Daily Living, Humans, Medicine, In patient, Aged, biology, business.industry, Body Weight, Nutritional status, Middle Aged, Multiple System Atrophy, medicine.disease, Malnutrition, 030104 developmental biology, Endocrinology, Neurology, biology.protein, Female, Neurology (clinical), business, Body mass index, 030217 neurology & neurosurgery
Abstract

Introduction: The importance of nutritional management in neurodegenerative diseases is increasingly recognized in the clinical setting. However, few reports have examined the nutritional intake in patients with multiple system atrophy (MSA). Here, we investigated changes in daily caloric intake, body mass index (BMI) and nutritional status during the disease course of MSA. Methods: We performed a single-hospital study of 82 consecutive patients with probable MSA according to the consensus criteria. We determined daily caloric intake, the level of activities of daily living (ADL; independent, wheelchair-bound or bedridden) and BMI at the time of admission. Nutritional status was also evaluated using biochemical nutritional markers including serum albumin, total cholesterol and lymphocyte count. Results: Although daily caloric intake decreased with ADL level deterioration (p < 0.01), no significant differences were observed in BMI among ADL levels. Serum albumin also decreased with ADL deterioration (p < 0.01); however, no significant differences were observed for serum total cholesterol or lymphocyte count with respect to ADL level. Conclusion: We demonstrated that patients with advanced stage MSA may develop malnutrition in the absence of a decrease in BMI. Moreover, serum albumin level may be useful for evaluating nutritional changes in MSA patients.

Published
2016

2. Diffuse Brain Abnormalities in Myotonic Dystrophy Type 1 Detected by 3.0 T Proton Magnetic Resonance Spectroscopy

Author

Kouichirou Okamoto, Tsutomu Nakada, Yuhei Takado, Hironaka Igarashi, Masaki Ohkubo, Masatoyo Nishizawa, Takayoshi Shimohata, and Kenshi Terajima

Subjects
Adult, Male, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Pathology, medicine.medical_specialty, Proton Magnetic Resonance Spectroscopy, Creatine, Myotonic dystrophy, chemistry.chemical_compound, Glutamatergic, Humans, Myotonic Dystrophy, Medicine, business.industry, Glutamate receptor, Brain, medicine.disease, Pathophysiology, Glutamine, Neurology, chemistry, Frontal lobe, Gliosis, Female, Neurology (clinical), medicine.symptom, business
Abstract

Patients with myotonic dystrophy type 1 (DM1) (n = 14) were compared with healthy controls (n = 13) using 3.0 T proton magnetic resonance spectroscopy (1H-MRS) to investigate brain pathophysiology. 1H-MRS imaging revealed reduced N-acetylaspartate to creatine ratio (NAA/Cr) in multiple brain regions (average 24%), suggesting diffuse brain abnormalities among patients with DM1. Single-voxel 1H-MRS among patients with DM1 showed (1) reduced NAA in both the frontal cortex (23%) and frontal white matter (31%) and unaltered myo-inositol, suggesting neuronal abnormalities without significant gliosis; and (2) elevated glutamine in the frontal cortex (36%) and reduced glutamate in the frontal white matter (20%) among patients with DM1, suggesting abnormalities in the glutamatergic system in the brain of patients with DM1. We consider that these results reflect brain abnormalities that cannot be detected by neuropathological assessment in patients with DM1.

Published
2015

3. Cerebral vasculopathy showing moyamoya-like changes in a patient with CREST syndrome

Author

Takashi Minakawa, Masatoshi Watanabe, Kenshi Terajima, Hideaki Ishiguro, Takayoshi Shimohata, Akira Hasegawa, Takashi Suzuki, and Kouichi Hirota

Subjects
CREST Syndrome, Systemic disease, Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Diagnostico diferencial, Angiography, Digital Subtraction, Middle Aged, medicine.disease, Cerebral Angiography, Central nervous system disease, Neurology, Ischemic Attack, Transient, Angiography, medicine, Humans, Female, Neurology (clinical), Moyamoya Disease, business
Published
2001

4. Novel Mutation in EIF2B Gene in a Case of Adult-Onset Leukoencephalopathy with Vanishing White Matter

Author

Osamu Onodera, Koichi Ishizu, Hiroshi Shibasaki, Yoshihiro Takayama, Masatoyo Nishizawa, Takayoshi Shimohata, Yukio Miki, Hidenao Fukuyama, Masaru Matsui, Hiroaki Ohtake, and Kotaro Mizutani

Subjects
Pediatrics, medicine.medical_specialty, Neurology, business.industry, Brain research, medicine.disease, humanities, Leukoencephalopathy with vanishing white matter, medicine, Neurology (clinical), business, Novel mutation, Neuroscience, geographic locations
Abstract

Departments of a Neurology and b Nuclear Medicine and Diagnostic Imaging and c Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto , d Department of Neurology, Sakakibara Hakuho Hospital, Mie , Departments of e Neurology and f Molecular Neuroscience, Brain Research Institute, Niigata University, Niigata , and g Department of Speech Physiology, Graduate School of Medicine, University of Tokyo, Tokyo , Japan

Published
2006

5. Contents Vol. 56, 2006

Author

D. Khandelwal, Roberto D’Alessandro, Nobuo Itoh, Antoine Maubon, Martine Barthelet, F. Segnarbieux, Sergio P. Rigonatti, Sien-Tsong Chen, U.K. Misra, Friedrich Goetz, Hélène Thibault, Norbert Nighoghossian, S. Cakmak, Sugata Takahashi, J.M.S. Pearce, N.K. Sethi, Giovanni Castelnovo, Zhi Liu, Jong S. Kim, Paulo S. Boggio, Hsiu-Chuan Wu, Tsong-Hai Lee, José Manuel Suárez-Peñaranda, Fernando Vázquez, Hideo Shinoda, Felipe Fregni, J. Torgovnick, Fumitake Gejo, Jong-Ho Park, Geneviève Derumeaux, Aleš Bartoš, R. Thukral, Dolores Dapena, Fernanda Martins Maia, Anja Windhagen, Setsu Sawai, Naoki Kawaguchi, Egberto Reis Barbosa, Byung-Woo Yoon, Chantal Nemoz, Anne Lefloch, Hideaki Nakayama, Shigeki Kuzuhara, N. Nighoghossian, Gilles Rioufol, Kazuaki Kanai, Chi-Jen Chen, Yi-Chun Chen, Manuel Arias, Angel Prieto, Takashi Ito, Gérard Finet, Hiroki Tsukada, Hyung-Min Kwon, Yugo Narita, Georg Berding, Tatsuya Yamamoto, Ryuji Sakakibara, François Chapuis, L. Derex, Masaykuki Maeda, Masatoyo Nishizawa, P.K. Sethi, Takamichi Hattori, Tomoyuki Uchiyama, Andrea Stracciari, Maria Guarino, S. Cartalat, Susana Arias-Rivas, Françoise Chapon, Michel Ovize, B. Nader, M. Hermier, Elke Wiesemann, Angel Sesar, Jeong-Min Kim, Takayoshi Shimohata, Miseon Kwon, Yutaka Naito, Felix Bermpohl, J. Honnorat, L. Mechtouff, Alvaro Pascual-Leone, Pierre Labauge, Valérie Rigau, Laurent Derex, Elisa Baldin, and J. Kalita

Subjects
Neurology, Neurology (clinical)
Published
2006

6. Isolated Trochlear Nerve Palsy in CREST Syndrome

Author

Masahiro Suzuki, Takayoshi Shimohata, Susumu Yamamoto, Toshiya Sato, Yasuhisa Akaiwa, and Yoko Yamamoto

Subjects
CREST Syndrome, Pathology, medicine.medical_specialty, Palsy, business.industry, Trochlear nerve, Trochlear nerve paralysis, Anatomy, Middle Aged, Trochlear Nerve Diseases, Neurology, medicine, Humans, Cranial nerve disease, Female, Neurology (clinical), medicine.symptom, business
Published
2003

7. Subject Index Vol. 56, 2006

Author

Tsong-Hai Lee, Hsiu-Chuan Wu, Alvaro Pascual-Leone, Susana Arias-Rivas, Françoise Chapon, Pierre Labauge, F. Segnarbieux, Valérie Rigau, J. Kalita, Laurent Derex, Elisa Baldin, Anja Windhagen, M. Hermier, Angel Sesar, Chantal Nemoz, Geneviève Derumeaux, Nobuo Itoh, Antoine Maubon, Shigeki Kuzuhara, Byung-Woo Yoon, J. Torgovnick, N.K. Sethi, S. Cakmak, Andrea Stracciari, Hideo Shinoda, Takayoshi Shimohata, U.K. Misra, Hyung-Min Kwon, Setsu Sawai, Hélène Thibault, Fernando Vázquez, J. Honnorat, B. Nader, R. Thukral, Martine Barthelet, Sien-Tsong Chen, L. Derex, Dolores Dapena, Jeong-Min Kim, Giovanni Castelnovo, Takamichi Hattori, Masatoyo Nishizawa, Egberto Reis Barbosa, Yugo Narita, Zhi Liu, Ryuji Sakakibara, Masaykuki Maeda, Kazuaki Kanai, Miseon Kwon, Fumitake Gejo, Angel Prieto, Takashi Ito, Manuel Arias, Tomoyuki Uchiyama, Felix Bermpohl, Hiroki Tsukada, P.K. Sethi, Roberto D’Alessandro, Aleš Bartoš, Maria Guarino, Gérard Finet, Georg Berding, Tatsuya Yamamoto, Naoki Kawaguchi, Fernanda Martins Maia, Sergio P. Rigonatti, Yi-Chun Chen, Friedrich Goetz, N. Nighoghossian, François Chapuis, Norbert Nighoghossian, J.M.S. Pearce, Jong S. Kim, Felipe Fregni, Paulo S. Boggio, José Manuel Suárez-Peñaranda, Anne Lefloch, S. Cartalat, L. Mechtouff, Michel Ovize, Elke Wiesemann, Yutaka Naito, Chi-Jen Chen, D. Khandelwal, Sugata Takahashi, Jong-Ho Park, Hideaki Nakayama, and Gilles Rioufol

Subjects
Gerontology, Index (economics), Neurology, Subject (documents), Neurology (clinical), Psychology
Published
2006

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