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Chronotype is defined as individual circadian preference, most often represented on the continuum between two extremes: morningness and eveningness. Growing number of studies show associations between circadian preference and various psychopathological symptoms. Eveningness has been shown to be related with depressiveness in non-clinical population, while mornigness has been presented as protective factor. Schizotypy is a schizophrenic-spectrum personality trait linked with a tendency to eccentricity, magical thinking and unusual experiences. Features of schizotypy has been identified in patients with mood disorders i.e bipolar disorder. While there is growing number of studies evaluating associations between chronotype and affective symptons, to our best knowledge there are no studies adressing the issue of association between schizotypy and circadian preferences. A total of 887 healthy individuals took part in the web-based study. Chronotype has been assessed with the use of Composite Scale of Morningness. Schizotypy has been measured with the use of the enlarged version of The Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE). Analysis revealed significant positive correlations between cognitive disorganization, introvertive/anhedonia, implusiveness/nonconformity and eveningness. To our best knowledge, results indicate for the first time relationship between eveningness and schizotypy, measured by O-LIFE.Disclosure of interestThe authors have not supplied their declaration of competing interest.

IntroductionSchizophrenia (SZ) patients present subtle motor deficits known as Neurological Soft Signs (NSS). Those deficits encompass impairments of motor coordination, sequencing of complex motor acts and sensory integration. It has been shown that SZ patients present also deficits of higher motor functions as implicit motor learning. Growing number of studies indicate that both NSS and implicit motor learning deficits are associated with impairments of common cortico-cerebellar pathways, however relationship between these two deficits has not been evaluated yet.ObjectivesTo assess NSS and implicit motor learning in SZ patients.AimsTo evaluate associations between NSS and implicit motor learning scores in SZ patients.MethodsTwenty schizophrenia patients and 20 healthy controls were examined. Patients were under olanzapine, clozapine or quetiapine treatment. NSS were assessed with Neurological Evaluation Scale (NES). Implicit motor learning were assessed with a use of Serial Reaction Time Task.ResultsSZ patients presented statistically higher NSS scores than healthy controls (P < 0.001) and presented no signs of implicit motor learning. There was statistically significant negative correlation between implicit motor learning score and total score of neurological soft signs (r = −0.44), sequence of motor acts subscore (r = −0.54) and sensory integration subscore (r = −0.47) in SZ patients group (P < 0.05).ConclusionsThere is association between implicit motor learning deficits and neurological soft signs in SZ patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Introduction Neurological soft signs (NSS) refer to the subtle dysfunctions of motor coordination, sequencing of complex motor acts and sensory integration. NSS are linked with schizophrenia and bipolar disorder, contributing to common biological background of those diseases. Growing number of studies present that both disorders share various functional and structural cerebellar dysfunctions, however schizophrenia and bipolar disorder have not been compared yet in terms of cerebellar motor dysfunctions. Objectives To assess neurological and cerebellar soft signs in schizophrenia and bipolar disorder Aim To evaluate whether both disorders share similar rate of neurological and cerebellar soft signs Methods 29 patients with schizophrenia, 30 bipolar disorder patients and 24 healthy controls were examined. Patients were under olanzapine, clozapine or quetiapine treatment. In case of BD patients mood stabilizer has been permitted. NSS were assessed with Neurological Evaluation Scale (NES). Cerebellar soft signs were evaluated by International Co-operative Ataxia Rating Scale (ICARS). Results Schizophrenia and bipolar disorder patients did not differ significantly in NES and ICARS total scores nor in any of their subscales. Both schizophrenia and bipolar disorder patients presented statistically higher total NES and ICARS scores than healthy controls (p Conclusions Both schizophrenia and bipolar disorder patients reveal similar motor dysfunctions in terms of neurological and cerebellar soft signs.