1. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography.
- Author
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Zhu, Chengcheng, Tian, Bing, Leach, Joseph R, Liu, Qi, Lu, Jianping, Chen, Luguang, Saloner, David, and Hope, Michael D
- Subjects
Humans ,Aortic Aneurysm ,Abdominal ,Thrombosis ,Disease Progression ,Contrast Media ,Imaging ,Three-Dimensional ,Magnetic Resonance Imaging ,Retrospective Studies ,Reproducibility of Results ,Aged ,Middle Aged ,Female ,Male ,Computed Tomography Angiography ,Abdominal aortic aneurysm surveillance ,CT angiography ,Diameter measurement ,Intraluminal thrombus composition ,Non-contrast MRI ,Biomedical Imaging ,Rare Diseases ,Clinical Research ,Cardiovascular ,4.2 Evaluation of markers and technologies ,Detection ,screening and diagnosis ,Clinical Sciences ,Nuclear Medicine & Medical Imaging - Abstract
ObjectivesManagement of abdominal aortic aneurysms (AAAs) is based on diameter. CT angiography (CTA) is commonly used, but requires radiation and iodinated contrast. Non-contrast MRI is an appealing alternative that may allow better characterization of intraluminal thrombus (ILT). This study aims to 1) validate non-contrast MRI for measuring AAA diameter, and 2) to assess ILT with CTA and MRI.Method28 patients with AAAs (diameter 50.7 ± 12.3 mm) underwent CTA and non-contrast MRI. MRI was acquired at 3 T using 1) a conventional 3D gradient echo (GRE) sequence and 2) a 3D T1-weighted black blood fast-spin-echo sequence. Two radiologists independently measured the AAA diameter. The ratio of signal of ILT and adjacent psoas muscle (ILTr = signalILT/signalMuscle) was quantified.ResultsStrong agreement between CTA and non-contrast MRI was shown for AAA diameter (intra-class coefficient > 0.99). Both approaches had excellent inter-observer reproducibility (ICC > 0.99). ILT appeared homogenous on CTA, whereas MRI revealed compositional variations. Patients with AAAs ≥5.5 cm and
- Published
- 2017