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Your search keyword '"PM2.5 ABSORBENCY"' showing total 2 results
Start Over Descriptor "PM2.5 ABSORBENCY" Journal european respiratory journal
2 results on '"PM2.5 ABSORBENCY"'

1. Air pollution exposure and lung function until age 16 years

Author

Milanzi, Edith B, Koppelman, Gerard H, Smit, Henriette A, Wijga, Alet H, Oldenwening, Marieke, Vonk, Judith M, Brunekreef, Bert, Gehring, Ulrike, One Health Chemisch, dIRAS RA-2, LS IRAS EEPI ME (Milieu epidemiologie), One Health Chemisch, dIRAS RA-2, LS IRAS EEPI ME (Milieu epidemiologie), and Groningen Research Institute for Asthma and COPD (GRIAC)

Subjects
Male, Vital capacity, Cross-sectional study, CHILDREN, NO2, chemistry.chemical_compound, 0302 clinical medicine, Interquartile range, USE REGRESSION-MODELS, Forced Expiratory Volume, AREAS, Medicine, Lung volumes, 030212 general & internal medicine, Longitudinal Studies, Child, Netherlands, Air Pollutants, ASSOCIATION, respiratory system, FUNCTION GROWTH, Respiratory Function Tests, PM2.5 ABSORBENCY, Female, HEALTH, Pulmonary and Respiratory Medicine, Adolescent, Nitrogen Dioxide, 03 medical and health sciences, FEV1/FVC ratio, PM10, Soot, Humans, Nitrogen dioxide, Particle Size, Asthma, STABILITY, business.industry, Environmental Exposure, Airway obstruction, Models, Theoretical, medicine.disease, respiratory tract diseases, Cross-Sectional Studies, 030228 respiratory system, chemistry, Linear Models, Particulate Matter, business, Demography
Abstract

Evidence for the effects of air pollution exposure on lung function growth into adolescence is scarce. We investigated associations of air pollution exposure with lung function and lung function growth until age 16.We conducted both longitudinal (n=915) and cross-sectional (n=721) analyses of associations of air pollution exposure with forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) growth from ages eight to 16 and FEV1 and FVC at age 16. We estimated residential concentrations of nitrogen dioxide (NO2), “soot” and particulate matter (PMx, where x is the 50% cut-off aerodynamic diameter in µm) with diameters of 2.5), 10) and 2.5–10 µm (PMcoarse) during the preschool, primary school and secondary school time windows by land use regression models. Associations with (growth in) FEV1 and FVC were analysed by linear (mixed effects) regression.Higher air pollution exposure was associated with reduced FEV1 growth (e.g. adjusted difference −0.26% (95% CI −0.49 to −0.03%) per interquartile range increase in secondary school PM2.5) and lower FEV1 (adjusted difference −2.36% (95% CI −3.76 to −0.94%)), but was not adversely associated with FVC. Associations with FEV1 were stronger in boys than girls and were not modified by asthma status.Higher air pollution exposure may lead to increased airway obstruction, but not reduced lung volume in adolescence.

Published
2018
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2. A multicentre study of air pollution exposure and childhood asthma prevalence: the ESCAPE project

Author

Mölter, Anna, Simpson, Angela, Berdel, Dietrich, Brunekreef, Bert, Custovic, Adnan, Cyrys, Josef, de Jongste, Johan, de Vocht, Frank, Fuertes, Elaine, Gehring, Ulrike, Gruzieva, Olena, Heinrich, Joachim, Hoek, Gerard, Hoffmann, Barbara, Klümper, Claudia, Korek, Michal, Kuhlbusch, Thomas A J, Lindley, Sarah, Postma, Dirkje, Tischer, Christina, Wijga, Alet, Pershagen, Göran, Agius, Raymond, IRAS RATIA2, Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), IRAS RATIA2, Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Pediatrics, Public Health, and Groningen Research Institute for Asthma and COPD (GRIAC)

Subjects
Male, Pulmonary and Respiratory Medicine, Pediatrics, medicine.medical_specialty, Nitrogen Dioxide, Air pollution, medicine.disease_cause, Logistic regression, NO2, Cohort Studies, chemistry.chemical_compound, USE REGRESSION-MODELS, PARTICULATE MATTER, Air Pollution, Germany, Environmental health, Wheeze, AREAS, Prevalence, medicine, Humans, Nitrogen dioxide, Child, NITROGEN-DIOXIDE, Netherlands, Vehicle Emissions, Asthma, Sweden, Inhalation Exposure, BIRTH COHORT, business.industry, Particulates, medicine.disease, LONG-TERM EXPOSURE, LUNG-FUNCTION, England, chemistry, PM2.5 ABSORBENCY, Cohort, Regression Analysis, Female, Nitrogen Oxides, medicine.symptom, business, CHILDRENS RESPIRATORY SYMPTOMS, Biologie, Environmental Monitoring, Cohort study
Abstract

The aim of this study was to determine the effect of six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameter 10), PM2.5, coarse particulate matter and PM2.5 absorbance) on childhood asthma and wheeze prevalence in five European birth cohorts: MAAS (England, UK), BAMSE (Sweden), PIAMA (the Netherlands), GINI and LISA (both Germany, divided into north and south areas).Land-use regression models were developed for each study area and used to estimate outdoor air pollution exposure at the home address of each child. Information on asthma and current wheeze prevalence at the ages of 4–5 and 8–10 years was collected using validated questionnaires. Multiple logistic regression was used to analyse the association between pollutant exposure and asthma within each cohort. Random-effects meta-analyses were used to combine effect estimates from individual cohorts.The meta-analyses showed no significant association between asthma prevalence and air pollution exposure (e.g. adjusted OR (95%CI) for asthma at age 8–10 years and exposure at the birth address (n=10377): 1.10 (0.81–1.49) per 10 μg·m-3 nitrogen dioxide; 0.88 (0.63–1.24) per 10 μg·m-3 PM10; 1.23 (0.78–1.95) per 5 μg·m-3 PM2.5). This result was consistently found in initial crude models, adjusted models and further sensitivity analyses.This study found no significant association between air pollution exposure and childhood asthma prevalence in five European birth cohorts.

Published
2015

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