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Background: In the 2014 GOLD update high symptom groups are defined based either on the CCQ or the CAT. The current standard of health status measurement in clinical trials is the SGRQ, this is however due to its length difficult to use in daily practice. As alternative CCQ and CAT have been proposed. So far no data has been published demonstrating the correlation between the German versions of the CCQ and CAT and the SGRQ Methods 346 COPD patients underwent a 3-week intensive rehabilitation programme. At baseline the patients completed the CAT, CCQ and SGRQ. Pearson correlations between the questionnaires were calculated. Results Data from N=307 patients could be included. 64.5% were male, mean age of 57.3 (6.9) years, mean FEV1 50.2%pred, 38.2% GOLD II, 37.9% GOLDIII, 23.9% GOLDIV. All correlations were significant (p0,8. Discussion There is a high correlation between the German versions of the CCQ and CAT and with SGRQ as standard. Both CCQ and CAT are quick and valid alternatives for the longer SGRQ in evaluating health status using the German language. (Table Presented).

Background: COPD is a major public health problem. Health status has become an important tool in its diagnostics and management with CCQ, CAT and SGRQ as the main instruments. Important is to what extent a change in its score is clinically relevant. The Minimal Clinically Important Difference (MCID) defines this. Current MCIDs are 0.4 (CCQ), 2.0 (CAT) and 4.0 (SGRQ). This study investigated the MCID of these tools using multiple approaches, since existing evidence is limited. Methods: In total 316 patients participated in a 3-week Pulmonary Rehabilitation programme (63% male, 51%FEV1pred., 41 mean packyears, 58 years mean age, 2/50/38/10% GOLD stage I/II/III/IV). Anchor-based approaches, including patient-referencing, criterion-referencing and questionnaire-referencing, and the distribution-based methods SEM and 0.5SD were used to determine the MCID. Results: Discussion: This study showed that the MCID of a tool might differ depending on which method is used. Estimates ranged from 0.30 to 0.51 for CCQ, from 2.17 to 3.50 for CAT and from 6.17 to 7.92 for SGRQ. The current published MCID of the CCQ fits well in this range, however the MCID of the CAT and SGRQ in the literature is below the range found. (Table Presented).

Background: COPD is a major public health problem. Health status has become an important tool in its diagnostics and management with CCQ, CAT and SGRQ as the main instruments. Important is to what extent a change in its score is clinically relevant. The Minimal Clinically Important Difference (MCID) defines this. Current MCIDs are 0.4 (CCQ), 2.0 (CAT) and 4.0 (SGRQ). This study investigated the MCID of these tools using multiple approaches, since existing evidence is limited. Methods: In total 316 patients participated in a 3-week Pulmonary Rehabilitation programme (63% male, 51%FEV1pred., 41 mean packyears, 58 years mean age, 2/50/38/10% GOLD stage I/II/III/IV). Anchor-based approaches, including patient-referencing, criterion-referencing and questionnaire-referencing, and the distribution-based methods SEM and 0.5SD were used to determine the MCID. Results: Discussion: This study showed that the MCID of a tool might differ depending on which method is used. Estimates ranged from 0.30 to 0.51 for CCQ, from 2.17 to 3.50 for CAT and from 6.17 to 7.92 for SGRQ. The current published MCID of the CCQ fits well in this range, however the MCID of the CAT and SGRQ in the literature is below the range found. (Table Presented).

Background: In the 2014 GOLD update high symptom groups are defined based either on the CCQ or the CAT. The current standard of health status measurement in clinical trials is the SGRQ, this is however due to its length difficult to use in daily practice. As alternative CCQ and CAT have been proposed. So far no data has been published demonstrating the correlation between the German versions of the CCQ and CAT and the SGRQ Methods 346 COPD patients underwent a 3-week intensive rehabilitation programme. At baseline the patients completed the CAT, CCQ and SGRQ. Pearson correlations between the questionnaires were calculated. Results Data from N=307 patients could be included. 64.5% were male, mean age of 57.3 (6.9) years, mean FEV1 50.2%pred, 38.2% GOLD II, 37.9% GOLDIII, 23.9% GOLDIV. All correlations were significant (p0,8. Discussion There is a high correlation between the German versions of the CCQ and CAT and with SGRQ as standard. Both CCQ and CAT are quick and valid alternatives for the longer SGRQ in evaluating health status using the German language. (Table Presented).