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Gut regulatory peptides bombesin (BBS) and neurotensin (NT) exert a wide spectrum of biological actions on gastrointestinal tissues and researchers have previously shown that they improve intestinal barrier function and oxidative stress in experimentally jaundiced rats. In the present study, we explored their potential action on liver histology and oxidative status in bile duct ligated rats. direct inhibitor of NF-kB, had any effect on this lack of apoptotic response to TGF-b when the complete medium was present observed in neoplastic tumours. Researchers have found that TGF-b induced cell-cycle arrest in all types of cultures independently of the tumoral origin hyperplastic, neoplastic or metastatic. This result was in contrast with results reported for other epithelial tumours.