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Start Over Author "Oliver, Tim" Journal european urology
7 results on '"Oliver, Tim"'

1. European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part I

Author

Krege, Susanne, Beyer, Jörg, Souchon, Rainer, Albers, Peter, Albrecht, Walter, Algaba, Ferran, Bamberg, Michael, Bodrogi, István, Bokemeyer, Carsten, Cavallin-Ståhl, Eva, Classen, Johannes, Clemm, Christoph, Cohn-Cedermark, Gabriella, Culine, Stéphane, Daugaard, Gedske, De Mulder, Pieter H.M., De Santis, Maria, de Wit, Maike, de Wit, Ronald, Derigs, Hans Günter, Dieckmann, Klaus-Peter, Dieing, Annette, Droz, Jean-Pierre, Fenner, Martin, Fizazi, Karim, Flechon, Aude, Fosså, Sophie D., Garcia del Muro, Xavier, Gauler, Thomas, Geczi, Lajos, Gerl, Arthur, Germa-Lluch, Jose Ramon, Gillessen, Silke, Hartmann, Jörg T., Hartmann, Michael, Heidenreich, Axel, Hoeltl, Wolfgang, Horwich, Alan, Huddart, Robert, Jewett, Michael, Joffe, Johnathan, Jones, William G., Kisbenedek, László, Klepp, Olbjørn, Kliesch, Sabine, Koehrmann, Kai Uwe, Kollmannsberger, Christian, Kuczyk, Markus, Laguna, Pilar, Leiva Galvis, Oscar, Loy, Volker, Mason, Malcolm D., Mead, Graham M., Mueller, Rolf, Nichols, Craig, Nicolai, Nicola, Oliver, Tim, Ondrus, Dalibor, Oosterhof, Gosse O.N., Paz Ares, Luis, Pizzocaro, Giorgio, Pont, Jörg, Pottek, Tobias, Powles, Tom, Rick, Oliver, Rosti, Giovanni, Salvioni, Roberto, Scheiderbauer, Jutta, Schmelz, Hans-Ulrich, Schmidberger, Heinz, Schmoll, Hans-Joachim, Schrader, Mark, Sedlmayer, Felix, Skakkebaek, Niels E., Sohaib, Aslam, Tjulandin, Sergei, Warde, Padraig, Weinknecht, Stefan, Weissbach, Lothar, Wittekind, Christian, Winter, Eva, Wood, Lori, and von der Maase, Hans

Published
2008
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4. Locally Advanced and Metastatic Prostate Cancer Treated with Intermittent Androgen Monotherapy or Maximal Androgen Blockade: Results from a Randomised Phase 3 Study by the South European Uroncological Group

Author

Silva, Fernando Calais da, primary, Silva, Fernando Manuel Calais da, additional, Gonçalves, Frederico, additional, Santos, Américo, additional, Kliment, Jan, additional, Whelan, Peter, additional, Oliver, Tim, additional, Antoniou, Nicos, additional, Pastidis, Spiro, additional, Marques Queimadelos, Anton, additional, and Robertson, Chris, additional

Published
2014
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6. Corrigendum to: “European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part I” [Eur Urol 2008;53:478–96] and to: “European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part II” [Eur Urol 2008;53:497–513]

Author

Krege, Susanne, primary, Beyer, Jörg, additional, Souchon, Rainer, additional, Albers, Peter, additional, Albrecht, Walter, additional, Algaba, Ferran, additional, Bamberg, Michael, additional, Bodrogi, István, additional, Bokemeyer, Carsten, additional, Cavallin-Ståhl, Eva, additional, Classen, Johannes, additional, Clemm, Christoph, additional, Cohn-Cedermark, Gabriella, additional, Culine, Stéphane, additional, Daugaard, Gedske, additional, De Mulder, Pieter H.M., additional, De Santis, Maria, additional, de Wit, Maike, additional, de Wit, Ronald, additional, Derigs, Hans Günter, additional, Dieckmann, Klaus-Peter, additional, Dieing, Annette, additional, Droz, Jean-Pierre, additional, Fenner, Martin, additional, Fizazi, Karim, additional, Flechon, Aude, additional, Fosså, Sophie D., additional, Garcia del Muro, Xavier, additional, Gauler, Thomas, additional, Geczi, Lajos, additional, Gerl, Arthur, additional, Germa-Lluch, Jose Ramon, additional, Gillessen, Silke, additional, Hartmann, Jörg T., additional, Hartmann, Michael, additional, Heidenreich, Axel, additional, Hoeltl, Wolfgang, additional, Horwich, Alan, additional, Huddart, Robert, additional, Jewett, Michael, additional, Joffe, Johnathan, additional, Jones, William G., additional, Kisbenedek, László, additional, Klepp, Olbjørn, additional, Kliesch, Sabine, additional, Koehrmann, Kai Uwe, additional, Kollmannsberger, Christian, additional, Kuczyk, Markus, additional, Laguna, Pilar, additional, Galvis, Oscar Leiva, additional, Loy, Volker, additional, Mason, Malcolm D., additional, Mead, Graham M., additional, Mueller, Rolf, additional, Nichols, Craig, additional, Nicolai, Nicola, additional, Oliver, Tim, additional, Ondrus, Dalibor, additional, Oosterhof, Gosse O.N., additional, Ares, Luis Paz, additional, Pizzocaro, Giorgio, additional, Pont, Jörg, additional, Pottek, Tobias, additional, Powles, Tom, additional, Rick, Oliver, additional, Rosti, Giovanni, additional, Salvioni, Roberto, additional, Scheiderbauer, Jutta, additional, Schmelz, Hans-Ulrich, additional, Schmidberger, Heinz, additional, Schmoll, Hans-Joachim, additional, Schrader, Mark, additional, Sedlmayer, Felix, additional, Skakkebaek, Niels E., additional, Sohaib, Aslam, additional, Tjulandin, Sergei, additional, Warde, Padraig, additional, Weinknecht, Stefan, additional, Weissbach, Lothar, additional, Wittekind, Christian, additional, Winter, Eva, additional, Wood, Lori, additional, and von der Maase, Hans, additional

Published
2008
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7. Locally advanced and metastatic prostate cancer treated with intermittent androgen monotherapy or maximal androgen blockade: results from a randomised phase 3 study by the South European Uroncological Group.

Author

Calais da Silva F, Calais da Silva FM, Gonçalves F, Santos A, Kliment J, Whelan P, Oliver T, Antoniou N, Pastidis S, Marques Queimadelos A, and Robertson C

Subjects
Adenocarcinoma blood, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Cyproterone Acetate administration & dosage, Disease Progression, Europe, Humans, Male, Middle Aged, Prostate-Specific Antigen blood, Prostatic Neoplasms blood, Quality of Life, Sexuality, Survival Rate, Time Factors, Triptorelin Pamoate administration & dosage, Adenocarcinoma drug therapy, Adenocarcinoma secondary, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Prostatic Neoplasms drug therapy, Prostatic Neoplasms pathology
Abstract

Background: Few randomised studies have compared antiandrogen intermittent hormonal therapy (IHT) with continuous maximal androgen blockade (MAB) therapy for advanced prostate cancer (PCa)., Objective: To determine whether overall survival (OS) on IHT (cyproterone acetate; CPA) is noninferior to OS on continuous MAB., Design, Setting, and Participants: This phase 3 randomised trial compared IHT and continuous MAB in patients with locally advanced or metastatic PCa., Intervention: During induction, patients received CPA 200 mg/d for 2 wk and then monthly depot injections of a luteinising hormone-releasing hormone (LHRH; triptoreline 11.25 mg) analogue plus CPA 200 mg/d. Patients whose prostate-specific antigen (PSA) was <4 ng/ml after 3 mo of induction treatment were randomised to the IHT arm (stopped treatment and restarted on CPA 300 mg/d monotherapy if PSA rose to ≥20 ng/ml or they were symptomatic) or the continuous arm (CPA 200 mg/d plus monthly LHRH analogue)., Outcome Measurements and Statistical Analysis: Primary outcome measurement was OS. Secondary outcomes included cause-specific survival, time to subjective or objective progression, and quality of life. Time off therapy in the intermittent arm was recorded., Results and Limitations: We recruited 1045 patients, of which 918 responded to induction therapy and were randomised (462 to IHT and 456 to continuous MAB). OS was similar between groups (p=0.25), and noninferiority of IHT was demonstrated (hazard ratio [HR]: 0.90; 95% confidence interval [CI], 0.76-1.07). There was a trend for an interaction between PSA and treatment (p=0.05), favouring IHT over continuous therapy in patients with PSA ≤1 ng/ml (HR: 0.79; 95% CI, 0.61-1.02). Men treated with IHT reported better sexual function. Among the 462 patients on IHT, 50% and 28% of patients were off therapy for ≥2.5 yr or >5 yr, respectively, after randomisation. The main limitation is that the length of time for the trial to mature means that other therapies are now available. A second limitation is that T3 patients may now profit from watchful waiting instead of androgen-deprivation therapy., Conclusions: Noninferiority of IHT in terms of survival and its association with better sexual activity than continuous therapy suggest that IHT should be considered for use in routine clinical practice., (Copyright © 2013 European Association of Urology. Published by Elsevier B.V. All rights reserved.)

Published
2014
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