1. The sexually dimorphic on the Y-chromosome gene (sdY) is a conserved male-specific Y-chromosome sequence in many salmonids
- Author
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Alexis Fostier, Edwige Quillet, Elodie Jouanno, Ayaka Yano, Yann Guiguen, René Guyomard, Barbara Nicol, Station commune de Recherches en Ichtyophysiologie, Biodiversité et Environnement (SCRIBE), Institut National de la Recherche Agronomique (INRA)-IFR140, Génétique Animale et Biologie Intégrative (GABI), Institut National de la Recherche Agronomique (INRA)-AgroParisTech, This study was supported by funds from the Institut National de la Recherche Agronomique (INRA), the Agence Nationale de la Recherche (ANR Blanc SVSE 7 2011, project SDS) and the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No. 222719-LIFECYCLE., Guiguen, Yann, Laboratoire de Physiologie et Génomique des Poissons (LPGP), and Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Recherche Agronomique (INRA)
- Subjects
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences ,0106 biological sciences ,déterminisme génétique ,salmonid ,Locus (genetics) ,Sexing ,Biology ,Y chromosome ,010603 evolutionary biology ,01 natural sciences ,03 medical and health sciences ,déterminisme du sexe ,salmonids ,Genetics ,14. Life underwater ,Gene ,Ecology, Evolution, Behavior and Systematics ,030304 developmental biology ,salmonidae ,locus ,0303 health sciences ,molecular sexing ,sex-determination locus ,sex-determining gene ,sdy ,Sexual dimorphism ,Conserved Synteny ,Original Article ,sexage ,Rainbow trout ,marqueur moléculaire ,General Agricultural and Biological Sciences ,Heterogametic sex - Abstract
Chantier qualité GA; All salmonid species investigated to date have been characterized with a male heterogametic sex-determination system. However, as these species do not share any Y-chromosome conserved synteny, there remains a debate on whether they share a common master sex-determining gene. In this study, we investigated the extent of conservation and evolution of the rainbow trout (Oncorhynchus mykiss) master sex-determining gene, sdY (sexually dimorphic on the Y-chromosome), in 15 different species of salmonids. We found that the sdY sequence is highly conserved in all salmonids and that sdY is a male-specific Y-chromosome gene in the majority of these species. These findings demonstrate that most salmonids share a conserved sex-determining locus and also strongly suggest that sdY may be this conserved master sex-determining gene. However, in two whitefish species (subfamily Coregoninae), sdY was found both in males and females, suggesting that alternative sex-determination systems may have also evolved in this family. Based on the wide conservation of sdY as a male-specific Y-chromosome gene, efficient and easy molecular sexing techniques can now be developed that will be of great interest for studying these economically and environmentally important species.
- Published
- 2012
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