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The average blood lactic acid in 7 cases of preeclampsia was 12.9 mg % (8.0-18.6) as compared with 11.0 mg % (9.1-12.3) in 8 cases of normal pregnancy. The average blood acetone bodies in the pre-eclamptic cases was 0.8 mg % (<0.1-2.6) as compared with 1.3 mg % (<0.1-2.7) for normal pregnancy. The average blood uric acid for the pre-eclamptic group was 4.5 mg % and for normal pregnancy was 3.0 mg %. The rise in blood lactic acid in eclampsia occurs mainly after convulsions. The hyperuricemia of pre-eclampsia and eclampsia can not be primarily attributed to an elevation of blood lactic acid or acetone bodies.