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The segmentation of dermoscopic‐based skin lesion images is considered to be challenging owing to various factors. Some of the most tangible reasons include poor contrast near the affected skin lesion, the fuzzy and unpredictable lesion limits, the presence of variations in noise, and capturing images under different conditions. This paper aims to develop an efficient segmentation model for dermoscopic images of different skin lesions based on deep learning. This paper proposes the 11‐layer convolutional deep neural network with two segmentation models trained from start to finish and do not depend on any previous information about the data. The viability, efficiency, and speculation ability of the models are evaluated on the ISIC2018 database. The proposed model achieves 0.903 accuracy and 0.820 Jaccard index in the segmentation of skin lesions. The model shows better performance compared to other image segmentation techniques from the leaderboards of ISIC2018 using deep learning. [ABSTRACT FROM AUTHOR]