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Driver pathways have been acknowledged to play critical roles in the initiation and progression of cancers►hence it is essential for precision medicine related studies to develop accurate and efficient methods to identify them. Although previous approaches have shown promising results by integrating multi-omics data, their preset artificial parameters may decrease the convenience to use and limit the application scalability. In this paper, a novel integration approach is proposed to incorporate four omics data, i.e., construct a weighted non-binary mutation matrix without presetting artificial parameters. A parameter-free identification model is put forward based on it. It takes advantage of the association between genes in the PPI network as well as balances the contribution of coverage and mutual exclusivity with the harmonic mean. Furthermore, a cooperative co-evolution algorithm is proposed for solving this model. In the algorithm, a particle swarm optimization algorithm suitable for solving combinatorial problems is presented. Three cooperative operators are devised to construct the cooperation among the populations and the swarm to increase the population diversity. Both real biological datasets and simulated ones were exerted to perform experimental comparisons among the proposed method and six other state-of-the-art ones. The gene sets identified by the presented method generally contain more genes involved in known signaling pathways than those obtained by the other methods. Simultaneously, both high accuracy and high efficiency of the proposed method were verified in experiments, making it practical in realistic applications and an effective supplementary tool to identify driver pathways. • A non-binary mutation matrix is constructed without artificial adjustable parameters. • The model incorporates gene association and balances coverage and mutual exclusivity. • A PSO algorithm suitable for solving combinatorial problems is presented. • A co-operative co-evolution algorithm is put forward for solving the presented model. • The performance is compared among the proposed method and seven state of the art ones. [ABSTRACT FROM AUTHOR]

• Optimal foraging algorithm with direction prediction & Gaussian oscillation is built. • New algorithm includes two update methods: prediction model and random model. • Prediction model mends exploitation ability by predicting the evolutionary direction. • Random model mends exploration by exploring the space with Gaussian distribution. • The superiority of algorithm is verified on benchmark set and engineering problems. Optimal foraging algorithm (OFA) is a newly stochastic optimization technique and is famous for its computational accuracy. However, the high computational accuracy leads to slow convergence speed. Experimental results demonstrate that OFA is good at unimodal functions but poor at multimodal functions. To improve these drawbacks, in this paper a novel modified OFA with direction prediction and Gaussian oscillation, named OFA/P&G is introduced. In OFA/P&G, a transition matrix is constructed when a new global optimum is found to generate the candidate individuals. If the current global optimum does not change, the Gaussian oscillation is employed in a low probability and OFA update method is used in a high probability to generate the candidate individuals. The superior performance of OFA/P&G is verified on the 12 CEC2017 benchmark functions, 13 constrained benchmark functions and 5 engineering problems. Experimental results demonstrate that OFA/P&G outperforms other comparative algorithms. Finally, a real-world problem, drilling path optimization, is solved by OFA/P&G. [ABSTRACT FROM AUTHOR]

Abstract: This paper presents combination of differential evolution (DE) and biogeography-based optimization (BBO) algorithm to solve complex economic emission load dispatch (EELD) problems of thermal generators of power systems. Emission substances like NO X , SO X , COX, Power demand equality constraint and operating limit constraint are considered here. Differential evolution (DE) is one of the very fast and robust, accurate evolutionary algorithms for global optimization and solution of EELD problems. Biogeography-based optimization (BBO) is another new biogeography inspired algorithm. Biogeography deals with the geographical distribution of different biological species. This algorithm searches for the global optimum mainly through two steps: migration and mutation. In this paper combination of DE and BBO (DE/BBO) is proposed to accelerate the convergence speed of both the algorithm and to improve solution quality. To show the advantages of the proposed algorithm, it has been applied for solving multi-objective EELD problems in a 3-generator system with NO X and SO X emission, in a 6-generators system considering NO X emission, in a 6-generator system addressing both valve-point loading and NO X emission. The current proposal is found better in terms of quality of the compromising and individual solution obtained. [Copyright &y& Elsevier]

In this paper, a new compact algorithm is proposed. Two sinusoidal formulas are used to automatically adjust the crossover rate and the mutation scaling factor in the compact Differential Evolution (cDE) metaheuristic. The proposed algorithm, called Compound Sinusoidal cDE, CScDE, is compared to seven state-of-the-art compact algorithms on the well-known BBOB test-bed, the CEC-2014 test suite for continuous optimisation, as well as five real-world optimisation problems chosen from the CEC-2011 benchmarks. The CScDE algorithm outperformed its competitors for most problem categories and over most dimensions. It is also compared to some well-established population-based metaheuristics. • A compact compound sinusoidal differential evolution, CScDE, is proposed. • CScDE uses sinusoidal formulas to adjust the parameters of compact DE. • Both binomial and exponential crossover are tested. • CScDE is applied on 89 reference problems with several dimensions. • CScDE outperformed state-of-the-art compact algorithms. [ABSTRACT FROM AUTHOR]

Moth–Flame Optimization (MFO) algorithm is widely used to solve real parameter global optimization problems. However, the original MFO algorithm has some problems. First, the global search ability of the algorithm is insufficient due to the lack of high-quality flames or the lack of diversity of the population. Moreover, due to the reduction of the number of flames mechanism and the simple transverse orientation flight mode of moths, the algorithm is easy to fall into local optimum. To overcome these difficulties, a new MFO called ODSFMFO is proposed in this paper, which consists of an improved flame generation mechanism based on Opposition-Based Learning (OBL) and Differential Evolution (DE) algorithm, and an enhanced local search mechanism based on Shuffled Frog Leaping Algorithm (SFLA) and death mechanism. The ODSFMFO firstly obtains a high-quality population through opposition-based learning, then enhances the diversity of the population through differential evolution algorithm, to improve the global search ability of the algorithm, and then, employs an improved shuffled frog leaping algorithm as a local search algorithm, and uses the death mechanism to eliminate the individuals with low fitness value, which not only make the algorithm easy to jump out of the local optimum, but also further improve the convergence speed. To demonstrate the effectiveness of the proposed algorithm, the ODSFMFO and other fourteen well-known optimization algorithms are tested and compared on 28 benchmark tasks of CEC 2013 and 30 benchmark tasks of CEC 2017. Simulation results show that the proposed algorithm obtains better results compared with other competitive algorithms. • An improved flame generation mechanism of MFO is proposed. • A new updating mechanism of SFLA is proposed to improve the local search ability. • The SFLA and death mechanism are applied in combination to MFO. • ODSFMFO is better than 14 compared algorithms. [ABSTRACT FROM AUTHOR]

Abstract: This paper proposes an optimization-based model for generic document summarization. The model generates a summary by extracting salient sentences from documents. This approach uses the sentence-to-document collection, the summary-to-document collection and the sentence-to-sentence relations to select salient sentences from given document collection and reduce redundancy in the summary. To solve the optimization problem has been created an improved differential evolution algorithm. The algorithm can adjust crossover rate adaptively according to the fitness of individuals. We implemented the proposed model on multi-document summarization task. Experiments have been performed on DUC2002 and DUC2004 data sets. The experimental results provide strong evidence that the proposed optimization-based approach is a viable method for document summarization. [Copyright &y& Elsevier]

Abstract: The sale of electric energy generated by photovoltaic (PV) plants has attracted much attention in recent years. The installation of PV plants aims to obtain the maximum benefit of captured solar energy. The current methodologies for planning the design of the different components of a PV plant are not completely efficient. This paper addresses the optimization of the design of PV plants with solar tracking, which consists of the optimization of the variables that make up the PV plant to obtain the minimum electric (Joule) losses possible. These variables are the size and distribution of solar modules in the solar tracker, the distribution of the solar trackers in the field and the choice of inverter. Evolutionary algorithms (EAs) are adaptive methods based on natural evolution that may be used for searching and optimization. Four different EAs have been used for optimizing the design of PV plants: steady-state genetic algorithm, generational genetic algorithm, CHC algorithm and DE algorithm. In order to test the performance of these algorithms we have used different proposed fields to mount PV plants. The results obtained show that EAs, and specifically DE with rand mutation schemes, are promising techniques to optimize design of PV plants. Furthermore, the results are contrasted with nonparametric statistical tests to support our conclusions. [Copyright &y& Elsevier]

Abstract: The differential evolution (DE) is a global optimization algorithm to solve numerical optimization problems. Recently the quantum-inquired differential evolution (QDE) has been proposed for binary optimization. This paper proposes DE/QDE to learn the Takagi–Sugeno (T–S) fuzzy model. DE/QDE can simultaneously optimize the structure and the parameters of the model. Moreover a new encoding scheme is given to allow DE/QDE to be easily performed. The two benchmark problems are used to validate the performance of DE/QDE. Compared to some existing methods, DE/QDE shows the competitive performance in terms of accuracy. [Copyright &y& Elsevier]

Abstract: This paper proposes new Differential Evolution (DE) algorithm, named as Chaotically Initialized Differential Evolution (CIDE), that uses chaotic maps with certainty, ergodicity, unpredictability, non-periodicity, complex temporal behavior and the stochastic property for initial population generation. This has been done by using of different chaotic number generators each time a random number is needed by the classical DE algorithm in its initial step. Seven chaotic maps have been analyzed in the benchmark functions. It has been detected that coupling emergent results in different areas, like those of DE and complex dynamics, can improve the quality of results in some optimization problems and also that chaos may be a desired process. It has been also shown that, Sinus map and Circle map have somewhat increased the solution quality, that is in some cases they improved the global searching capability by escaping the local solutions. [Copyright &y& Elsevier]

Abstract: Dynamic economic dispatch (DED) plays an important role in power system operation, which is a complicated nonlinear constrained optimization problem. It has non-smooth and non-convex characteristic when generation unit valve-point effects are taken into account. This paper proposes a novel hybrid method to solve DED problem with valve-point effects, by integrating an improved differential evolution(IDE) with the Shor’s r-algorithm. The proposed method is developed in such a way that IDE is applied as a based level search, which can give a good direction to the optimal global region, and a local search Shor’s r-algorithm is used as a fine tuning to determine the optimal solution at the final. A feasibility-based selection comparison technique and a heuristic rule are devised to handle constraints effectively in IDE, which does not require penalty factors or any extra parameters and can guide the population to the feasible region quickly. The feasibility and effectiveness of the proposed hybrid method is demonstrated for an application example and the test results are compared with those of other methods. It is shown that the proposed method is capable of yielding higher quality solutions. [Copyright &y& Elsevier]

• A new multi-objective optimization method used OBL strategy, WOA and DE algorithms • It combines DE and the OBL to improve the performance of the WOA • The MWDEO results outperformed all other algorithms in most of the test problems • 32 multi-objective test problems are used in the experiments and CEC2017 problems The optimization problems are divided into a single objective and multi-objective. Single objective optimization has only one objective function; whereas, multi-objective optimization has multiple objective functions that generate the Pareto set; therefore, solving a multi-objective problem is a challenging problem. This paper presents a new multi-objective optimization method (called MWDEO) based on improved whale optimization algorithm (WOA) by combining the differential evolution (DE) algorithm and the opposition-based learning (OBL). The MWDEO uses the WOA to perform a global exploration, whereas DE is used to exploit the search space; while the OBL is applied to improve the exploration and exploitation by generating the opposite values. The proposed algorithm is evaluated using 32 multi-objective test problems besides a set of benchmark problems of CEC'2017. The experimental results are compared with nine state-of-the-art multi-objective methods. The analysis of the results showed that the proposed MWDEO outperformed all other algorithms in most of the test problems which indicates that the proposed MWDEO is competitive and effective in solving different types of multi-objective problems. [ABSTRACT FROM AUTHOR]