52 results on '"Silke, John"'
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2. Faculty Opinions recommendation of Von Hippel-Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein.
3. Faculty Opinions recommendation of Optimization of a series of RIPK2 protacs.
4. Faculty Opinions recommendation of Clinical positioning of the IAP antagonist tolinapant (ASTX660) in colorectal cancer.
5. Faculty Opinions recommendation of Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
6. Faculty Opinions recommendation of DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability.
7. Faculty Opinions recommendation of Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells.
8. Faculty Opinions recommendation of SUMOs Mediate the Nuclear Transfer of p38 and p-p38 during Helicobacter Pylori Infection.
9. Faculty Opinions recommendation of p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.
10. Faculty Opinions recommendation of Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS.
11. Faculty Opinions recommendation of RIOK-1 Is a Suppressor of the p38 MAPK Innate Immune Pathway in Caenorhabditis elegans.
12. Faculty Opinions recommendation of p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.
13. Faculty Opinions recommendation of Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome.
14. Faculty Opinions recommendation of Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length.
15. Faculty Opinions recommendation of Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.
16. Faculty Opinions recommendation of Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.
17. Faculty Opinions recommendation of Metabolic benefits of inhibition of p38α in white adipose tissue in obesity.
18. Faculty Opinions recommendation of The role of TTP phosphorylation in the regulation of inflammatory cytokine production by MK2/3.
19. Faculty Opinions recommendation of Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.
20. Faculty Opinions recommendation of Effective Pro-Inflammatory Induced Activity of GALT, a Conserved Antigen in A. pleuropneumoniae, Improves the Cytokines Secretion of Macrophage via p38, ERK1/2 and JNK MAPKs Signal Pathway.
21. Faculty Opinions recommendation of A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics.
22. Faculty Opinions recommendation of Intrafibrillar silicified collagen scaffold promotes in-situ bone regeneration by activating the monocyte p38 signaling pathway.
23. Faculty Opinions recommendation of TAB1-Induced Autoactivation of p38α Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185.
24. Faculty Opinions recommendation of Prions activate a p38 MAPK synaptotoxic signaling pathway.
25. Faculty Opinions recommendation of Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER).
26. Faculty Opinions recommendation of The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells.
27. Faculty Opinions recommendation of Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.
28. Faculty Opinions recommendation of Apoptosis in infection.
29. Faculty Opinions recommendation of Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture.
30. Faculty Opinions recommendation of Somatic mutant clones colonize the human esophagus with age.
31. Faculty Opinions recommendation of Delineating the role of cooperativity in the design of potent PROTACs for BTK.
32. Faculty Opinions recommendation of Stat3-mediated alterations in lysosomal membrane protein composition.
33. Faculty Opinions recommendation of Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.
34. Faculty Opinions recommendation of TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.
35. Faculty Opinions recommendation of Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.
36. Faculty Opinions recommendation of Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.
37. Faculty Opinions recommendation of Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.
38. Faculty Opinions recommendation of Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.
39. Faculty Opinions recommendation of Mass Cytometric Analysis Reveals Viable Activated Caspase-3+ Luminal Progenitors in the Normal Adult Human Mammary Gland.
40. Faculty Opinions recommendation of Inflammatory memory sensitizes skin epithelial stem cells to tissue damage.
41. Faculty Opinions recommendation of The evolution of the host microbiome as an ecosystem on a leash.
42. Faculty Opinions recommendation of Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.
43. Faculty Opinions recommendation of Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
44. Faculty Opinions recommendation of A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.
45. Faculty Opinions recommendation of The BH3-only protein Bad is dispensable for TNF-mediated cell death.
46. Faculty Opinions recommendation of Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
47. Faculty Opinions recommendation of Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
48. Faculty Opinions recommendation of Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure.
49. Faculty Opinions recommendation of RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.
50. Faculty Opinions recommendation of Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.
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