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Your search keyword '"Ning Zhou"' showing total 1 results
Start Over Author "Ning Zhou" Topic gene expression Journal faseb journal
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1. Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock.".

Author

Ying-Hui Wu, Fischer, David F., Kalsbeek, Andries, Garidou-Boof, Marie-Laure, Van Der Vliet, Jan, Van Heijningen, Caroline, Rong-Yu Liu, Jiang-Ning Zhou, and Swaab, Dick F.

Subjects
ALZHEIMER'S disease, PINEAL gland, GENE expression, PATIENTS, SUPRACHIASMATIC nucleus
Abstract

This article presents a study on the effect of Alzheimer disease (AD) and the underlying mechanisms on pineal clock gene expression. Certain diurnal rhythmic expression is lost in the pineal gland of preclinical and clinical AD patients. Clock gene alterations similar as the AD pineal is shown in rat pineal deprived of suprachiasmatic nucleus control. Conclusion of the study is given.

Published
2006
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