1. Characterization of a protein that appears in the nervous system of the mothManduca sextacoincident with neuronal death
- Author
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Edward J. Roy, Carol S. Giometti, Susan E. Fahrbach, and Michelle E. Montemayor
- Subjects
Nervous system ,Aging ,Abdominal ganglia ,Moths ,Nervous System ,Biochemistry ,0302 clinical medicine ,Structural Biology ,Protein biosynthesis ,Electrophoresis, Gel, Two-Dimensional ,media_common ,Neurons ,Gel electrophoresis ,0303 health sciences ,biology ,respiratory system ,Cell biology ,medicine.anatomical_structure ,Ecdysis ,Cell death ,medicine.medical_specialty ,animal structures ,Cell Survival ,Sphingidae ,media_common.quotation_subject ,Neuronal death ,Biophysics ,Nerve Tissue Proteins ,Manduca sexta ,03 medical and health sciences ,Internal medicine ,Genetics ,medicine ,Animals ,Metamorphosis ,Molecular Biology ,030304 developmental biology ,fungi ,Cell Biology ,biology.organism_classification ,Molecular Weight ,Endocrinology ,Gel electrophoresis, 2-D ,Ganglia ,sense organs ,Neuron ,Protein synthesis ,030217 neurology & neurosurgery - Abstract
Two-dimensional gel electrophoresis was used to locate potential neuronal death-related proteins in the moth Manduca sexta. Protein patterns of ganglia of pharate adult moths (taken prior to adult ecdysis) compared with protein patterns of one-day-old adults revealed reproducible changes in protein patterns. An acidic protein of approximately 40000 Da was present in all samples from adult moths undergoing neuronal death and essentially absent from pharate adult samples.
- Published
- 1990
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