Author: "Kiyonari, Hiroshi" / Journal: febs letters - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Kiyonari, Hiroshi" Journal febs letters

Author: Kusano, Rie, primary, Fujita, Kousuke, additional, Shinoda, Yasuharu, additional, Nagaura, Yuko, additional, Kiyonari, Hiroshi, additional, Abe, Takaya, additional, Watanabe, Toshio, additional, Matsui, Yasuhisa, additional, Fukaya, Masahiro, additional, Sakagami, Hiroyuki, additional, Sato, Tatsuya, additional, Funahashi, Jun-ichi, additional, Ohnishi, Motoko, additional, Tamura, Shinri, additional, and Kobayashi, Takayasu, additional
Published: 2016
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Author: Hata, Kikumi, primary, Yanase, Noriko, additional, Sudo, Katsuko, additional, Kiyonari, Hiroshi, additional, Mukumoto, Yoshiko, additional, Mizuguchi, Junichiro, additional, and Yokosuka, Tadashi, additional
Published: 2016
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Author: Watanabe, Naoki, Hiramatsu, Kentaro, Miyamoto, Rieko, Yasuda, Kaoru, Suzuki, Norihiko, Oshima, Naoko, Kiyonari, Hiroshi, Shiba, Dai, Nishio, Saori, Mochizuki, Toshio, Yokoyama, Takahiko, Maruyama, Shoichi, Matsuo, Seiichi, Wakamatsu, Yuko, and Hashimoto, Hisashi
Published: 2009
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Author: Kusano, Rie, Fujita, Kousuke, Shinoda, Yasuharu, Nagaura, Yuko, Kiyonari, Hiroshi, Abe, Takaya, Watanabe, Toshio, Matsui, Yasuhisa, Fukaya, Masahiro, Sakagami, Hiroyuki, Sato, Tatsuya, Funahashi, Jun-ichi, Ohnishi, Motoko, Tamura, Shinri, and Kobayashi, Takayasu
Subjects: PHOSPHOPROTEIN phosphatases, BRAIN abnormalities, MITOGEN-activated protein kinases, CELLULAR signal transduction, LABORATORY mice
Abstract: PPM1L, a member of the metal-dependent protein phosphatase ( PPM) family, is involved in regulating the stress-activated protein kinase pathway and ceramide trafficking. However, the physiological function of PPM1L in the brain is unclear. In this study, we generated and analyzed ppm1l-deficient mice in order to investigate PPM1L functions in the brain. Our results indicate that ppm1l is highly expressed in the central nervous system during mouse development and that ppm1lΔ/Δ mice display impaired motor performance and morphological abnormalities in the forebrain. Electron microscopic and immunohistochemical analyses suggest that these abnormalities are due to impaired axonal tract formation. Our novel findings suggest an important role for PPM1L in brain development. [ABSTRACT FROM AUTHOR]
Published: 2016
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Author: Chan, Techuan, Kondow, Akiko, Hosoya, Akihiro, Hitachi, Keisuke, Yukita, Akira, Okabayashi, Koji, Nakamura, Hiroaki, Ozawa, Hidehiro, Kiyonari, Hiroshi, Michiue, Tatsuo, Ito, Yuzuru, and Asashima, Makoto
Published: 2007
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Author: Chan, Techuan, primary, Kondow, Akiko, additional, Hosoya, Akihiro, additional, Hitachi, Keisuke, additional, Yukita, Akira, additional, Okabayashi, Koji, additional, Nakamura, Hiroaki, additional, Ozawa, Hidehiro, additional, Kiyonari, Hiroshi, additional, Michiue, Tatsuo, additional, Ito, Yuzuru, additional, and Asashima, Makoto, additional
Published: 2007
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