1. Assessment of ovarian function with anti-Müllerian hormone in systemic lupus erythematosus patients undergoing hematopoietic stem cell transplant
- Author
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James H. Segars, Alan H. DeCherney, Rebecca Babb, Steven Z. Pavletic, Hyacinth Browne, Alicia Y. Armstrong, and Gabor G. Illei
- Subjects
Oncology ,Adult ,Anti-Mullerian Hormone ,medicine.medical_specialty ,endocrine system ,Adolescent ,medicine.medical_treatment ,Ovary ,Pilot Projects ,Hematopoietic stem cell transplantation ,Sensitivity and Specificity ,Article ,Follicle-stimulating hormone ,Young Adult ,Internal medicine ,medicine ,Humans ,Lupus Erythematosus, Systemic ,Ovarian reserve ,Retrospective Studies ,Chemotherapy ,biology ,Estradiol ,Reproduction ,Hematopoietic Stem Cell Transplantation ,Obstetrics and Gynecology ,Hematopoietic stem cell ,Anti-Müllerian hormone ,Menstruation ,medicine.anatomical_structure ,Reproductive Medicine ,Immunology ,biology.protein ,Female ,Stem cell ,Follicle Stimulating Hormone ,Biomarkers - Abstract
In this small pilot study, anti-Mullerian hormone (AMH) levels in women undergoing chemotherapy and hematopoietic stem cell transplantation facilitated earlier identification of impaired ovarian reserve compared with FSH and the resumption of menses. Larger studies are needed to accurately assess the clinical significance of AMH levels in the prediction of long-term reproductive outcomes in reproductive-age transplant patients with our current conditioning regimen.
- Published
- 2008