1. TAGLN expression is deregulated in endometriosis and may be involved in cell invasion, migration, and differentiation
- Author
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Gabriela dos Santos Hidalgo, Claudia Cristina Paro de Paz, Rui Alberto Ferriani, Júlio César Rosa e Silva, and Juliana Meola
- Subjects
Adult ,Cellular differentiation ,Endometriosis ,Muscle Proteins ,Biology ,Peritoneal Diseases ,law.invention ,Endometrium ,Young Adult ,Cell Movement ,law ,Gene expression ,medicine ,Humans ,Ovarian Diseases ,Eutopic endometrium ,Cytoskeleton ,Polymerase chain reaction ,Reverse Transcriptase Polymerase Chain Reaction ,Microfilament Proteins ,Obstetrics and Gynecology ,Cell Differentiation ,Cell migration ,Middle Aged ,medicine.disease ,Gene Expression Regulation ,Reproductive Medicine ,Cancer research ,Female ,TAGLN Gene - Abstract
We found an increased expression of the TAGLN gene in endometriotic lesions compared with the eutopic endometrium of the same patients by real-time polymerase chain reaction. It is possible that this deregulation contributes to the development and maintenance of endometriosis by being involved in the pathways of organization of cytoskeletal architecture.
- Published
- 2011
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