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Your search keyword '"Machado, María J."' showing total 2 results
Start Over Author "Machado, María J." Journal fetal diagnosis and therapy
2 results on '"Machado, María J."'

2. Effects of antenatal betamethasone on human fetal branch pulmonary artery flow velocity waveforms.

Author

Bartha JL, Largo-Heinrich M, Machado MJ, González-Bugatto F, and Hervías-Vivancos B

Subjects
Adolescent, Adult, Blood Flow Velocity drug effects, Blood Flow Velocity physiology, Female, Humans, Maternal-Fetal Exchange drug effects, Maternal-Fetal Exchange physiology, Pregnancy, Pregnancy Complications, Cardiovascular prevention & control, Pulmonary Artery physiology, Pulmonary Circulation drug effects, Pulmonary Circulation physiology, Ultrasonography, Doppler, Color methods, Betamethasone administration & dosage, Pregnancy Complications, Cardiovascular drug therapy, Prenatal Care methods, Pulmonary Artery drug effects
Abstract

Objective: To evaluate the effect of antenatal betamethasone on fetal branch pulmonary artery flow velocity waveforms., Methods: Betamethasone 12 mg i.m. in 2 injections 24 h apart was given to 25 pregnant women at risk of preterm delivery. Pulsatility (PI) and resistance (RI) indexes were measured at the proximal, middle and distal segments of the fetal pulmonary artery before and repeatedly 1, 2 and 7 days after the first dose. ANOVA for repeated measures and the general linear model were used to statistically analyze the results., Results: Blood flow resistance decreased after betamethasone treatment at both the middle (p = 0.001 and p = 0.02 for RI and PI, respectively) and the proximal (p = 0.03 for RI) segments returning to basal values after 7 days., Conclusions: Antenatal betamethasone decreases fetal branch pulmonary artery vascular resistance., ((c) 2007 S. Karger AG, Basel)

Published
2008
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