1. Diterpenoids from the twigs and leaves of Croton caudatus var. tomentosus.
- Author
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Song, Jin-Tong, Han, Yang, Wang, Xiao-Ling, Shen, Tao, Lou, Hong-Xiang, and Wang, Xiao-Ning
- Subjects
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ALTERNATIVE medicine , *ANTINEOPLASTIC agents , *BIOLOGICAL models , *BREAST tumors , *LEAVES , *LIVER tumors , *LUNG tumors , *MEDICINAL plants , *SPECTRUM analysis , *PHYTOCHEMICALS , *PLANT extracts , *DESCRIPTIVE statistics , *IN vitro studies , *PHARMACODYNAMICS ,CERVIX uteri tumors - Abstract
One new 9,10- seco -abietane derivative, crotontomentosin A ( 1 ), four new abietane-type diterpenoids, crotontomentosins B–E ( 2 – 5 ), one new ent -halimane-type diterpenoid, crotontomentosin F ( 6 ), along with five known diterpenoids ( 7 – 11 ) and one known sesquiterpenoid ( 12 ) were obtained from the twigs and leaves of Croton caudatus Geisel. var. tomentosus Hook. The structures of the compounds were established on the basis of extensive spectroscopic data. Compounds 1 – 4 and 11 exhibited moderate to weak inhibitory activity against the proliferation of the Hela, Hep G2, MDA-MB-231, or A549 cell lines selectively. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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