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Four new compounds, including three new spirostanol saponins [tupistroside G-I ( 1 – 3 )] and a new flavane- O -glucoside [tupichiside A ( 4 )], together with ten known compounds, were isolated from the fresh rhizomes of Tupistra chinensis . The structures of the new compounds were elucidated by spectroscopic analysis and chemical evidence. All compounds were tested in vitro for their cytotoxic activities against the Human LoVo and BGC-823 cell lines, and six of them were found to possess potent cytotoxicity. Compounds 2 , 8 and 9 showed significant cytotoxicity against the tested tumor cell lines with IC 50 values ranging from 0.2 to 0.9 μM. [ABSTRACT FROM AUTHOR]

Abstract: Four steroidal saponins were isolated from the leaves of Furcraea selloa var. marginata. These included one furostanol saponin, furcreafurostatin (1), and three known spirostanol saponins, furcreastatin (3), yuccaloeside C (4) and cantalasaponin-1 (5). The 22-O-methyl ether (2) of furcreafurostatin (1) was also characterized. The structures were determined by using a combination of spectroscopic techniques. [Copyright &y& Elsevier]

The phytochemical investigation of the aerial parts of Tribulus terrestris of Bulgarian origin has resulted in the isolation of the novel furostanol saponin 1, named tribol, together with the known spirostanol saponins 2 and 3 and sitosterol glucoside. The structure of tribol was determined as (25R)-furost-5(6)-ene-3β,16,26-triol-3-O-α-rhamnopyranosyl-(1→2)-[α-rhamnopyranosyl-(1→4)]-β-glucopyranoside (1) by spectral analysis, including extensive 1D and 2D-NMR experiments. [Copyright &y& Elsevier]