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Start Over Author "Wang, Zhiping" Topic apoptosis Journal food & chemical toxicology

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1 results on '"Wang, Zhiping"'

1. Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis.

Author

Yuan, Xuan, Li, Tao, Xiao, Erlong, Zhao, Hong, Li, Yongqian, Fu, Shengjun, Gan, Lu, Wang, Zhenhua, Zheng, Qiusheng, and Wang, Zhiping

Subjects
*CHALCONES, *BLADDER cancer, *APOPTOSIS, *CELL cycle, *CANCER cell proliferation, *MITOSIS, *ANTINEOPLASTIC agents, *IN vitro toxicity testing
Abstract

Highlights: [•] In this study, we found licochalcone B (LCB) could inhibit proliferation of T24 and EJ cells in vitro. [•] S-phase arrest and apoptosis involved in LCB’s antiproliferative effects. [•] Corresponding, we illustrated the possible mechanisms of LCB-induced S-phase arrest and apoptosis. [•] We also demonstrated the antitumor activity of LCB in vivo in MB49 (murine bladder cancer cell line) tumor model. [•] This was the first time to explore the effects of LCB on the bladder cancer cells. [ABSTRACT FROM AUTHOR]

Published
2014
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