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Milk minerals are not only essential components for human health, but they can be informative for milk quality and cow's health. Herein, we investigated the feasibility of Fourier Transformed mid Infrared (FTIR) spectroscopy for the prediction of a detailed panel of 17 macro, trace, and environmental elements in bovine milk, using partial least squares regression (PLS) and machine learning approaches. The automatic machine learning significantly outperformed the PLS regression in terms of prediction performances of the mineral elements. For macrominerals, the R 2 ranged from 0.59 to 0.78. Promising predictability was achieved for Cu and B (R 2  = 0.66 and 0.74, respectively) and more moderate ones for Fe, Mn, Zn, and Al (R 2 from 0.48 to 0.58). These results provide a reliable basis for a rapid and cost-effective quantification of these traits, serving as a resource for dairy farmers seeking to enhance the quality of milk production and optimize cheese properties., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Ltd.)