104 results on '"Van Remmen, Holly"'
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2. Scavenging lipid hydroperoxides by glutathione peroxidase 4 overexpression attenuates contractile and mitochondrial dysfunction in a murine model of accelerated sarcopenia.
3. Decreased mitochondrial respiration in cardiac fibers isolated from a mouse model of Friedreich’s ataxia
4. The Role of Oxylipins in Muscle Atrophy
5. Impact of elevated oxidative stress on mechanisms related to muscle force generation
6. Lipid hydroperoxides are key drivers of denervation-induced muscle atrophy
7. Down-regulation of the mitochondrial matrix peptidase ClpP in muscle cells causes mitochondrial dysfunction and decreases cell proliferation
8. Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts
9. Sod1 gene ablation in adult mice leads to physiological changes at the neuromuscular junction similar to changes that occur in old wild-type mice
10. Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria
11. ELEVATED OXIDATIVE STRESS IN MOTOR NEURONS INITIATES LOSS OF NEUROMUSCULAR JUNCTION STRUCTURE AND FUNCTION, MUSCLE WEAKNESS AND ATROPHY: P6
12. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress
13. Genetic ablation of 12/15-lipoxygenase but not 5-lipoxygenase protects against denervation-induced muscle atrophy
14. The effects of dietary restriction on oxidative stress in rodents
15. Transgenic expression of SOD1 specifically in neurons of Sod1 deficient mice prevents defects in muscle mitochondrial function and calcium handling
16. Neuron specific lack of SOD1 leads to accelerated age-related loss of NMJ structure
17. Complex IV Deficient Mice Develop Increased Adiposity and Insulin Resistance: 40
18. Trends in oxidative aging theories
19. The Effect of Skeletal Muscle Specific Mitochondrial Catalase (mmCAT) on Restoring Muscle Functions and Reducing Oxidative Stress in SOD1KO Mice
20. The lipid hydroperoxide scavenger liproxstatin-1 reduces denervation-induced muscle pathology
21. Unacylated Ghrelin Protects Against Neurogenic Atrophy and Contractile Dysfunction in a Redox-dependent Sarcopenia
22. Lack of SOD1 In Neuronal Tissue Affects Neuromuscular Junction Stability in Advanced Age
23. Dietary restriction attenuates the accelerated aging phenotype of Sod1−/− mice
24. Divergent Roles for 12/15-Lipoxygenase and 5-Lipoxygenase Lipid Metabolic Pathways in Neurogenic Muscle Atrophy: 299
25. Glutathione-peroxidase-1 null muscle progenitor cells are globally defective
26. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy
27. Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain
28. Mitochondria-Generated Oxidative Stress is Altered by Subcellular Localization of MsrA Overexpression: 345
29. Age-related Changes in Neurotrophic Factors Expression in Skeletal Muscle Undergoing Atrophy: 179
30. Disruption of the 12/15-Lipoxygenase Gene (Alox15) Protects Against Denervation-Induced Muscle Atrophy: 168
31. Increased mitochondrial matrix-directed superoxide production by fatty acid hydroperoxides in skeletal muscle mitochondria
32. Calorie Restriction (CR) Protects against Oxidative Stress-induced Muscle Atrophy by Preserving Mitochondrial Function and Muscle Integrity Even in the Absence of Antioxidant Enzyme CuZnSOD: 198
33. Reduction in Mitochondria H2O2 Ameliorates Age-associated Cognitive Impairment in Peroxiredoxin 3 Transgenic Mice: 186
34. Role of 12/15-lipoxygenase Pathway in Muscle Atrophy: 184
35. Probing the Surface of G93A and H46R/H48Q Mutant SOD1 Protein for Exposed Hydrophobic Residues and Monitoring Conformationally Altered Proteins in Mouse Models of ALS: 499
36. Glutathione Peroxidase 4 Differentially Regulates the Release of Apoptogenic Proteins from Mitochondria: 196
37. GAPDH: a Common Target Protein Affected Structurally and Functionally by Mutant SOD1 in Mouse Models of Familial Amyotrophic Lateral Sclerosis: 448
38. Superoxide DOES Matter in Amyotrophic Lateral Sclerosis: 445
39. PGC-1 Alpha Transgenic Mouse - a Unique Model for Aging Study: 398
40. Trx2 Haploinsufficiency in Trx2+/- Mice Results in Impaired Mitochondrial Function and Increased Sensitivity to Oxidative Stress: 369
41. Two Distinct Sites of Superoxide Production Within Complex I: 318
42. Glutathione Peroxidase 4 Regulates Oxidative Stress Induced Apoptosis in vivo by Suppressing Cardiolipin Peroxidation: 208
43. The In Vivo Gene Expression Signature of Oxidative Stress: 97
44. INTRACELLULAR ROS GENERATION BY CONTRACTING SKELETAL MUSCLE CELLS WITH DEFICIENT OR ENHANCED ANTIOXIDANT SYSTEMS: 391
45. THE CRITICAL ROLE OF GLUTATHIONE PEROXIDASE 4 IN ANTIOXIDANT DEFENSE: INSIGHTS FROM STUDYING Gpx4 TRANSGENIC AND KNOCKOUT MICE: 386
46. ABSENCE OF Cu,Zn-SOD CAUSES SEVERE OXIDATIVE STRESS AND ACCELERATION OF AGE-DEPENDENT SKELETAL MUSCLE ATROPHY: 348
47. DRASTIC INCREASE IN MITOCHONDRIAL ROS PRODUCTION DURING ALS: 404
48. OVEREXPRESSION OF GLUTATHIONE PEROXIDASE 4 PROTECTS MICE FROM OXIDATIVE STRESS INDUCED APOPTOSIS: 367
49. COMPLEX III RELEASES SUPEROXIDE TO BOTH SIDES OF THE INNER MITOCHONDRIAL MEMBRANE: 45
50. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
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