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Your search keyword '"Lotze, Michael T"' showing total 11 results
Start Over Author "Lotze, Michael T" Journal frontiers in immunology
11 results on '"Lotze, Michael T"'

2. Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer

Author

Dhupar, Rajeev, primary, Jones, Katherine E., additional, Powers, Amy A., additional, Eisenberg, Seth H., additional, Ding, Kai, additional, Chen, Fangyuan, additional, Nasarre, Cecile, additional, Cen, Zhanpeng, additional, Gong, Yi-Nan, additional, LaRue, Amanda C., additional, Yeh, Elizabeth S., additional, Luketich, James D., additional, Lee, Adrian V., additional, Oesterreich, Steffi, additional, Lotze, Michael T., additional, Gemmill, Robert M., additional, and Soloff, Adam C., additional

Published
2022
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4. Corrigendum: Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients

Author

Niu, Xuefeng, primary, Li, Song, additional, Li, Pingchao, additional, Pan, Wenjing, additional, Wang, Qian, additional, Feng, Ying, additional, Mo, Xiaoneng, additional, Yan, Qihong, additional, Ye, Xianmiao, additional, Luo, Jia, additional, Qu, Linbing, additional, Weber, Daniel, additional, Byrne-Steele, Miranda L., additional, Wang, Zhe, additional, Yu, Fengjia, additional, Li, Fang, additional, Myers, Richard M., additional, Lotze, Michael T., additional, Zhong, Nanshan, additional, Han, Jian, additional, and Chen, Ling, additional

Published
2020
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5. Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients

Author

Niu, Xuefeng, primary, Li, Song, additional, Li, Pingchao, additional, Pan, Wenjing, additional, Wang, Qian, additional, Feng, Ying, additional, Mo, Xiaoneng, additional, Yan, Qihong, additional, Ye, Xianmiao, additional, Luo, Jia, additional, Qu, Linbing, additional, Weber, Daniel, additional, Byrne-Steele, Miranda L., additional, Wang, Zhe, additional, Yu, Fengjia, additional, Li, Fang, additional, Myers, Richard M., additional, Lotze, Michael T., additional, Zhong, Nanshan, additional, Han, Jian, additional, and Chen, Ling, additional

Published
2020
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6. HMGB1 Promotes Myeloid Egress and Limits Lymphatic Clearance of Malignant Pleural Effusions

Author

Soloff, Adam C., primary, Jones, Katherine E., additional, Powers, Amy A., additional, Murthy, Pranav, additional, Wang, Yue, additional, Russell, Kira L., additional, Byrne-Steele, Miranda, additional, Lund, Amanda W., additional, Yuan, Jian-Min, additional, Monaco, Sara E., additional, Han, Jian, additional, Dhupar, Rajeev, additional, and Lotze, Michael T., additional

Published
2020
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8. Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine

Author

Murthy, Pranav, primary, Singhi, Aatur D., additional, Ross, Mark A., additional, Loughran, Patricia, additional, Paragomi, Pedram, additional, Papachristou, Georgios I., additional, Whitcomb, David C., additional, Zureikat, Amer H., additional, Lotze, Michael T., additional, Zeh III, Herbert J., additional, and Boone, Brian A., additional

Published
2019
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11. HMGB1: the central cytokine for all lymphoid cells.

Author

Guanqiao Li, Liang, Xiaoyan, Lotze, Michael T., Gadina, Massimo, and Querini, Patrizia Rovere

Subjects
CYTOKINES, CYTOSOL, T cells, B cells, TOLL-like receptors
Abstract

High-mobility group box 1 (HMGB1) is a leaderless cytokine, like the IL-1 and FGF family members, that has primary roles within the nucleus and the cytosol. Within the nucleus, it serves as another guardian of the genome, protecting it from oxidant injury and promoting access to transcriptional complexes such as nuclear hormone/nuclear hormone receptors and p53/p73 complexes. Within the cytosol it promotes autophagy and recruitment of the myddosome to Toll-like receptor (TLR) 9 vesicular compartments. Outside of the cell, it can either bind to specific receptors itself, or with high affinity to DNA, nucleosomes, IMp, lipopolysaccharide, and lipoteichoic acid to mediate responses in specific physiological or pathological conditions. Currently identified receptors include TLR2, TLR4, the receptor for advanced glycation end products, CD24-Siglec G/10, chemokine CXC receptor 4, and TIM-3. In terms of its effects or functions within lymphoid cells, HMGB1 is principally secreted from mature dendritic cells (DCs) to promote T-cell and B-cell reactivity and expansion and from activated natural killer cells to promote DC maturation during the afferent immune response. Some studies suggest that its primary role in the setting of chronic inflammation is to promote immunosuppression. As such, HMGB1 is a central cytokine for all lymphoid cells playing a role complementary to its better studied role in myeloid cells. [ABSTRACT FROM AUTHOR]

Published
2013
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