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BackgroundPain and gastrointestinal dysfunction after laparoscopic myomectomy (LM) are significant issues that prevent this procedure from being classified as a “Day Surgery.” This study aims to assess the effectiveness and safety of thumbtack needle acupuncture (TNA) combined with patient-controlled intravenous analgesia (PCIA) for promoting enhanced recovery after LM.MethodsA total of 52 patients were enrolled in the study, divided into a treatment group receiving TNA and a control group. Both groups were administered PCIA without background sufentanil. For rescue analgesia or antiemetic needs, a bolus infusion of flurbiprofen axetil (50 mg) or intravenous metoclopramide (10 mg) was provided. The primary outcomes measured were the Visual Analog Scale (VAS) scores at awakening, as well as at 36 h, 48 h, and 60 h after LM. Secondary outcomes included VAS scores at 6 h, 12 h, 24 h, and 72 h after LM, total sufentanil consumption, the number of PCIA analgesic requests (attempts), the number of doses of rescue flurbiprofen axel analgesia required, preoperative anxiety scores, gastrointestinal function recovery assessment, first ambulation time, length of hospital stay, and patient satisfaction. Adverse events were also recorded.ResultsCompared to the control group, the treatment group showed significantly lower VAS scores, fewer analgesia attempts, reduced total sufentanil consumption, and a smaller number of rescue analgesia doses after LM, along with lower preoperative anxiety scores and higher satisfaction with pain management (p