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Your search keyword '"Chung, Jong-Won"' showing total 12 results
Start Over Author "Chung, Jong-Won" Journal frontiers in neurology
12 results on '"Chung, Jong-Won"'

3. Association of Systolic Blood Pressure and Cerebral Collateral Flow in Acute Ischemic Stroke by Stroke Subtype

Author

Sim, Jae Eun, Chung, Jong-Won, Seo, Woo-Keun, Bang, Oh Young, and Kim, Gyeong-Moon

Subjects
Neurology, Neurology (clinical)
Abstract

Background and PurposeCollateral flow in acute ischemic stroke is known as a predictor of treatment outcome and long-term prognosis. However, factors determining the initial collateral flow remain unclear. We investigated factors related to collateral flow in patients with acute ischemic stroke caused by large vessel occlusion (AIS-LVO) and further analyzed the results according to stroke etiology.MethodsThis was a retrospective study using prospective stroke registry data from a single university hospital from October 2014 to May 2021. AIS-LVO with middle cerebral artery M1 occlusion identified by pre-treatment multiphasic computed tomography angiography was included. Collateral flow score was graded on a 6-point ordinal scale according to pial arterial filling.ResultsA total of 74 patients [cardioembolism (CE): 57; large artery atherosclerosis (LAA): 17] was included. The mean age of all patients was 72.2 ± 11.7 years, and 37.8 % (n = 28) were men. Multivariate regression analysis showed that initial SBP [odds ratio (OR): 0.994; 95% confidence interval (CI): 0.990–0.998; p = 0.002] and stroke etiology (OR: 0.718; 95% CI: 0.548–0.940; p = 0.019) were independent factors of the collateral flow grade. Collateral flow grade was independently associated with initial SBP in the CE group (OR: 0.993; 95% CI: 0.989–0.998; p = 0.004) but not in the LAA group (OR: 0.992; 95% CI: 0.980–1.004; p = 0.218). Initial SBP was significantly correlated with NIHSS score in the CE group but not in the LAA group (r2= 0.091, p = 0.023; r2 = 0.043, p = 0.426, respectively).ConclusionsElevated initial SBP was associated with poor cerebral collateral flow and more severe symptoms in the CE group, but not in the LAA group in patients with AIS-LVO. These findings suggest differential effects of initial SBP elevation on collateral flow by stroke subtypes.

Published
2022

5. Atrial Fibrillation Related and Unrelated Stroke Recurrence Among Ischemic Stroke Patients With Atrial Fibrillation

Author

Kim, Bum Joon, primary, Hwang, Yang-Ha, additional, Park, Man-Seok, additional, Kim, Joon-Tae, additional, Choi, Kang-Ho, additional, Jung, Jin-Man, additional, Yu, Sungwook, additional, Kim, Chi Kyung, additional, Oh, Kyungmi, additional, Song, Tae-Jin, additional, Kim, Yong-Jae, additional, Park, Kwang-Yeol, additional, Kim, Jeong-Min, additional, Park, Jong-Ho, additional, Choi, Jay Chol, additional, Chung, Jong-Won, additional, Bang, Oh Young, additional, Kim, Gyeong-Moon, additional, Heo, Sung Hyuk, additional, and Seo, Woo-Keun, additional

Published
2021
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7. Characteristics and Factors for Short-Term Functional Outcome in Stroke Patients With Atrial Fibrillation, Nationwide Retrospective Cohort Study

Author

Song, Tae-Jin, primary, Baek, In-Young, additional, Woo, Ho Geol, additional, Kim, Yong-Jae, additional, Chang, Younkyung, additional, Kim, Bum Joon, additional, Heo, Sung Hyuk, additional, Jung, Jin-Man, additional, Oh, Kyungmi, additional, Kim, Chi Kyung, additional, Yu, Sungwook, additional, Park, Kwang Yeol, additional, Kim, Jeong-Min, additional, Park, Jong-Ho, additional, Choi, Jay Chol, additional, Park, Man-Seok, additional, Kim, Joon-Tae, additional, Choi, Kang-Ho, additional, Hwang, Yang-Ha, additional, Chung, Jong-Won, additional, Bang, Oh Young, additional, Kim, Gyeong-Moon, additional, and Seo, Woo-Keun, additional

Published
2019
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11. Effect of Statins on Survival Following Stroke in Patients With Cancer

Author

Kim, Ye Sel, primary, Park, Moo-Seok, additional, Lee, Jun-Hwa, additional, Chung, Jong-Won, additional, Lee, Mi Ji, additional, Kim, Chi Kyung, additional, Jung, Jin-Man, additional, Oh, Kyungmi, additional, Bang, Oh Young, additional, Kim, Geong-Moon, additional, Choi, Ji-Mi, additional, Lee, Juneyoung, additional, Chung, Chin Sang, additional, Lee, Kwang Ho, additional, and Seo, Woo-Keun, additional

Published
2018
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12. Comparison of Clopidogrel and Ticlopidine/ Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting.

Author

Chung, Jong-Won, Kim, Suk Jae, Hwang, Jaechun, Lee, Mi Ji, Lee, Jun, Lee, Kyung-Yul, Park, Man-Seok, Sung, Sang Min, Kim, Keon Ha, Jeon, Pyoung, and Bang, Oh Young

Subjects
CLOPIDOGREL, TICLOPIDINE, GINKGO, CAROTID artery, CAROTID artery stenosis
Abstract

Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events. This study aimed to compare the effectiveness and safety of clopidogrel and ticlopidine plus Ginkgo biloba in clopidogrel-resistant patients undergoing CAS. Methods: In this multi-center, randomized, controlled trial, we used platelet reactivity test to select patients undergoing CAS who showed clopidogrel resistance, and compared treatments using clopidogrel and ticlopidine plus ginkgo. The primary outcome was the incidence of new ischemic lesion in the ipsilateral hemisphere of CAS. Detection of microembolic signal on transcranial Doppler was the secondary outcome. The clinical outcomes were also monitored. Results: This trial was discontinued after 42 patients were randomized after preplanned interim sample size re-estimation indicated an impractical sample size. The primary endpoint occurred in 12/22 patients (54.5%) in the clopidogrel group and 13/20 patients (65.0%) in the ticlopidine–ginkgo group (P = 0.610). No significant differences in the presence of microembolic signal (15.0 vs. 11.8%, P = 0.580), clinical outcomes (ischemic stroke or transient ischemic attack, 0.0 vs. 5.5%; acute myocardial infarction 0.0 vs. 0.0%; all-cause death, 4.5 vs. 0.0%), or incidence of adverse events were found in the two groups. In terms of resistance to clopidogrel, treatment with ticlopidine–ginkgo significantly increased the P2Y12 Reaction Units (difference, 0.0 [−0.3–3.0] vs. 21.0 [6.0–35.0], P < 0.001). Conclusions: In patients who showed clopidogrel resistance, ticlopidine–ginkgo treatment was safe and increased P2Y12 Reaction Units; however, compared to clopidogrel, it failed to improve surrogate and clinical endpoints in patients undergoing CAS. This multimodal biomarker-based clinical trial is feasible in neurointerventional research. Clinical Trial Registration: http://www.clinicaltrials.gov. Unique identifier: NCT02133989. [ABSTRACT FROM AUTHOR]

Published
2019
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