1. Surgical treatment for recurrent cholangiocarcinoma: a single-center series
- Author
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Laura Fernández, Mikel Gastaca, Eva Alonso, Mikel Prieto, Patricia Ruiz, Alberto Ventoso, Ibone Palomares, Arkaitz Perfecto, and Andrés Valdivieso
- Subjects
cholangiocarcinoma ,recurrence ,surgical treatment ,outcomes ,chemotherapy ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
PurposeThe present study aims to assess the results obtained after surgical treatment of cholangiocarcinoma (CC) recurrences.MethodsWe carried out a single-center retrospective study, including all patients with recurrence of CC. The primary outcome was patient survival after surgical treatment compared with chemotherapy or best supportive care. A multivariate analysis of variables affecting mortality after CC recurrence was performed.ResultsEighteen patients were indicated surgery to treat CC recurrence. Severe postoperative complication rate was 27.8% with a 30-day mortality rate of 16.7%. Median survival after surgery was 15 months (range 0-50) with 1- and 3-year patient survival rates of 55.6% and 16.6%, respectively. Patient survival after surgery or CHT alone, was significantly better than receiving supportive care (p< 0.001). We found no significant difference in survival when comparing CHT alone and surgical treatment (p=0.113). Time to recurrence of
- Published
- 2023
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