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Domination-type parameters are difficult to manage in Cartesian product graphs and there is usually no general relationship between the parameter in both factors and in the product graph. This is the situation of the domination number, the Roman domination number or the 2-domination number, among others. Contrary to what happens with the domination number and the Roman domination number, the 2-domination number remains unknown in cylinders, that is, the Cartesian product of a cycle and a path and in this paper, we will compute this parameter in the cylinders with small cycles. We will develop two algorithms involving the (min, +) matrix product that will allow us to compute the desired values of γ2(Cn□Pm), with 3 ≤ n ≤ 15 and m ≤ 2. We will also pose a conjecture about the general formula for the 2-domination number in this graph class. [ABSTRACT FROM AUTHOR]