1. Angiographic predictors of coronary hemodynamics
- Author
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Daniel Nour, Usaid Allahwala, Peter Hansen, Gemma A Figtree, Gregory Nelson, Michael Ward, and Ravinay Bhindi
- Subjects
Fractional Flow Reserve, Myocardial ,Cardiac Catheterization ,Predictive Value of Tests ,Coronary Stenosis ,Hemodynamics ,Molecular Medicine ,Humans ,Constriction, Pathologic ,Coronary Artery Disease ,Cardiology and Cardiovascular Medicine ,Coronary Angiography ,Coronary Vessels ,Severity of Illness Index - Abstract
Aims: Assess the correlation between diameter stenosis, lesion length, location, diffuse coronary disease and with fractional flow reserve (FFR). Methods/Results: We performed quantitative coronary analysis analysis on 384 lesions with stable coronary artery disease undergoing FFR assessment. Vessels were 59.1% left anterior descending artery (LAD), 16.1% left circumflex artery and 14.8% right coronary artery. Median diameter stenosis was 58% ± 2.5 and median lesion length was 10 mm ± 7.36. 21% of vessels were diffusely diseased. Lesions were 33.6% proximal, 44% mid-vessel and 12% distal. Median FFR was 0.85. Diameter stenosis correlated with lower FFR (p < 0.005, odds ratio [OR]: 2.4 [95% CI: 0.99–5.63]). There was no association between lesion length, location, number of proximal side branches and FFR. Vessels with diffuse disease had a nonsignificant trend for lower FFR (0.84 vs 0.85, p = 0.375, OR: 1.26 [95% CI: 0.76–2.09]). LAD lesions had significantly lower FFR compared with non-LAD (p < 0.001, OR: 2.55 [95% CI: 1.61–4.04]); including left circumflex artery and right coronary artery lesions (p = 0.001, OR: 3.4 [95% CI: 1.7–6.9]) and p = 0.02, OR: 2.55 [95% CI: 1.17–4.34]). Conclusion: FFR is not related to lesion length, location or number of proximal branches.
- Published
- 2022