1. FrAnTK: a Frequency-based Analysis ToolKit for efficient exploration of allele sharing patterns in present-day and ancient genomic datasets
- Author
-
J Víctor Moreno-Mayar
- Subjects
AcademicSubjects/SCI01140 ,population genomics ,AcademicSubjects/SCI00010 ,Population ,Computer programming ,QH426-470 ,ANCESTRY ,Biology ,Software and Data Resources ,AcademicSubjects/SCI01180 ,SEQUENCE ,Population genomics ,user-friendly pipeline ,Genetics ,education ,Molecular Biology ,Allele frequency ,ancient DNA ,Genetics (clinical) ,Alleles ,computer.programming_language ,education.field_of_study ,business.industry ,Data manipulation language ,Computational Biology ,Genomics ,Python (programming language) ,allele sharing statistics ,Data science ,Visualization ,python ,POPULATIONS ,AcademicSubjects/SCI00960 ,Perl ,business ,computer ,Software ,perl - Abstract
Present-day and ancient population genomic studies from different study organisms have rapidly become accessible to diverse research groups worldwide. Unfortunately, as datasets and analyses become more complex, researchers with less computational experience often miss their chance to analyze their own data. We introduce FrAnTK, a user-friendly toolkit for computation and visualization of allele frequency-based statistics in ancient and present-day genome variation datasets. We provide fast, memory-efficient tools that allow the user to go from sequencing data to complex exploratory analyses and visual representations with minimal data manipulation. Its simple usage and low computational requirements make FrAnTK ideal for users that are less familiar with computer programming carrying out large-scale population studies.
- Published
- 2021
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