1. [Two Cases of Locally Recurrent Rectal Cancer Successfully Treated by Carbon Ion Radiotherapy].
- Author
-
Kanehara K, Ohnuma S, Suzuki H, Yamamura A, Karasawa H, Kohyama A, Aoki T, Watanabe K, Tanaka N, Musha H, Motoi F, Kamei T, Naitoh T, and Unno M
- Subjects
- Chemoradiotherapy, Female, Humans, Middle Aged, Neoplasm Recurrence, Local, Positron Emission Tomography Computed Tomography, Heavy Ion Radiotherapy, Rectal Neoplasms diagnostic imaging, Rectal Neoplasms radiotherapy
- Abstract
Case 1: A female patient in her 60s underwent laparoscopic intersphincteric resection for rectal cancer. After 42 months, the serum level of carcinoembryonic antigen(CEA)was elevated, and PET-CT showed a locally recurrent rectal cancer that increased FDG-uptake. Carbon ion radiotherapy(CIRT)(73.6 GyE/16 Fr)was performed. Serum CEA level and FDG-uptake were normalized. No regrowth of tumor has been found for 12 months. Case 2: A female patient in her 60s underwent abdominoperineal resection for rectal cancer. After 42 months, the serum level of CEA was elevated, and CT revealed a local recurrence of rectal cancer. Subsequently, the tumor was resected; however, resection margin was microscopically positive. Therefore, chemoradiotherapy(S-1, 60 Gy)was performed. At 31 months after local resection, a re-recurrent tumor was noted in her left ischium. Therefore, CIRT(70.4 GyE/16 Fr)was performed. Serum CEA level and FDG-uptake were normalized. No regrowth of tumor has been found for 24 months. CIRT is an effective therapy for locally recurrent rectal cancer.
- Published
- 2018