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Your search keyword '"Nario, K."' showing total 2 results
Start Over Author "Nario, K." Journal gan to kagaku ryoho cancer chemotherapy
2 results on '"Nario, K."'

1. [Four cases of hypopharyngeal cancer treated with docetaxel, cisplatin, and 5-FU followed by radiotherapy and/or neck dissection].

Author

Miyahara H, Nario K, Matsushiro N, Sasai H, and Kajikawa H

Subjects
Aged, Antineoplastic Combined Chemotherapy Protocols adverse effects, Chemotherapy, Adjuvant, Cisplatin administration & dosage, Cisplatin adverse effects, Docetaxel, Drug Administration Schedule, Fluorouracil administration & dosage, Fluorouracil adverse effects, Humans, Hypopharyngeal Neoplasms surgery, Leukopenia chemically induced, Male, Middle Aged, Neck Dissection, Neoadjuvant Therapy, Prognosis, Radiotherapy Dosage, Taxoids administration & dosage, Taxoids adverse effects, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Hypopharyngeal Neoplasms drug therapy, Hypopharyngeal Neoplasms radiotherapy
Abstract

We treated 4 patients with hypopharyngeal cancer, each of whom had a complete response after 2 cycles of chemotherapy with docetaxel, cisplatin, and 5-FU followed by radiation and/or neck dissection. Twenty-one months to 2 years after this therapy, 3 patients had no recurrence and no metastasis with their laryngeal framework and function preserved. Chemotherapy including docetaxel, cisplatin, and 5-FU is a useful treatment for early head and neck cancer.

Published
2004

2. [A case of neck metastasis from hypopharyngeal carcinoma successfully treated with TS-1].

Author

Kajikawa H, Nario K, and Miyahara H

Subjects
Carcinoma, Squamous Cell secondary, Carcinoma, Squamous Cell surgery, Drug Administration Schedule, Drug Combinations, Humans, Hypopharyngeal Neoplasms pathology, Hypopharyngeal Neoplasms surgery, Lymph Nodes drug effects, Lymphatic Metastasis, Male, Middle Aged, Neck, Antimetabolites, Antineoplastic therapeutic use, Carcinoma, Squamous Cell drug therapy, Hypopharyngeal Neoplasms drug therapy, Lymph Nodes pathology, Oxonic Acid therapeutic use, Pyridines therapeutic use, Tegafur therapeutic use
Abstract

We report a case of hypopharyngeal carcinoma with recurrent neck metastasis. Preoperative chemoradiation and pharyngo-laryngo-esophagectomy with bilateral neck dissection was done as first-line therapy. Six months later, the carcinoma metastasized to the right paratracheal lymph node. Because of resistance to chemoradiation (CBDCA) as second-line therapy, we administered TS-1 for the treatment after 60 Gy radiation. The chemotherapy with TS-1 resulted in complete response by diagnostic imaging (CT). There was no sign of recurrence for 1 year after 5 courses of treatment. TS-1, which allows oral chemotherapy on an outpatient basis, would be a useful drug for treatment with radiotherapy in patients with advanced and/or recurrent head and neck cancer.

Published
2004

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